COURSE UNIT TITLE

: INDIVIDUALIZED MEDICINE AND TREATMENT METHODS IN CANCER

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
TRO 6015 INDIVIDUALIZED MEDICINE AND TREATMENT METHODS IN CANCER ELECTIVE 2 0 0 6

Offered By

Translational Oncology

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR DOCTOR YASEMIN BAŞBINAR

Offered to

Adeloscent and Young Adult Oncology PhD
Translational Oncology
Oncology Nursing
Translational Oncology

Course Objective

At the point where today's medicine, cancer-related methods to examine and discuss the concept of individualized medicine1

Learning Outcomes of the Course Unit

1   Acquire knowledge of Personalized cancer medicine on the basic applications of clinical studies.
2   Be able to know and apply methods for distinguishing individual differences
3   Be able to know the differences of metabolism between individuals and understand the importance of individualizing cancer treatment
4   Knowledgeable individualized medicine about cancer and treatment methods
5   Be able to know the differences of treatment outcomes
6   Acquire ability to practice of the personalized medicine laboratory techniques.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 The concept of the course and Individualized Medicine
2 Methods to measure of individual differences. Molecular diagnosis
3 Methods to measure of individual differences. Biomarkers
4 ndividual medicine-specific statistical concepts (concepts of sensitivity and specificity, , identification of predictive factors, profile analysis, risk id
5 The metabolic differences between individuals in the formation of cancer, prognosis and efficacy of treatment
6 The cell kinetics in cancer treatment and Individual approach
7 The choice of therapy and efficacy ( influence of factors such as age, performance status, socioeconomic status)
8 The rationale for individualizing cancer treatment
9 Treatment technologies provided by individual medicine (research on treatment techniques)-1
10 Treatment technologies provided by individual medicine (research on treatment techniques)-2
11 Treatment technologies provided by individual medicine (research on treatment techniques)-3
12 Treatment technologies provided by individual medicine (research on treatment techniques)-4
13 Translational Studies /Bed to bench, Individual medicine (Based on a clinical problem, the models applied in the laboratory, laboratory results of the adaptation of the clinic)1
14 Translational Studies /Bed to bench, Individual medicine (Based on a clinical problem, the models applied in the laboratory, laboratory results of the adaptation of the clinic)-2
15 Translational Studies /Bed to bench, Individual medicine (Based on a clinical problem, the models applied in the laboratory, laboratory results of the adaptation of the clinic)-3

Recomended or Required Reading

1. Pharmacogenomics and Personalized Medicine,Nadine Cohen, Humana Press; 1 ed, 2008
2.Genomic and Personalized Medicine, Two-Vol Set: V1-2, Huntington Ph.D Willard (Editor), Geoffrey S. Ginsburg (Editor) Academic Press; 1 edition, 2008
3.Textbook of Personalized Medicine, Kewal K. Jain, Springer, 1998
4.The Language of Life: DNA and the Revolution in Personalized Medicine ,Francis S. Collins, Harper, 2010
References: Baskın Y, Çalıbaşı G,"Kanser hastalarında farmakogenetik uygulamaları ve farmakoekonomi", Turk Hij Den Biyol Derg, 68/3/152-164/2011, 2011,
6.Baskın Y, Yigitbasi T,"Clinical Proteomics of Breast Cancer", Current Genomics, 11/7/528-536/2010
7. Baskın Y, Afacan G, Erkunt SS, Yiğitbaşı T,"A new method in systemic autoimmune diseases diagnosis: Multiplex test system and method performances", Turkish Journal of Biochemistry, 33/1/19- 24/2008
8. Y.BASKIN,"Tıpta Teknolojik Gelişimin Neden Olduğu Kavram Değişimleri: Kişiselleştirilmiş Tıp", Turkish Bulletion of Hygiene and Experimental Biology, 64/2/54-59/2007, 2007

Planned Learning Activities and Teaching Methods

Theoretical and applied Lectures, the topics in-class activities (presentations and assignments) to consolidate and discussion, laboratory applications, and application assignments

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 PRF PERFORMANCE
2 FIN FINAL EXAM
3 FCG FINAL COURSE GRADE PRF * 0.40 + FIN*0.60
4 RST RESIT
5 FCGR FINAL COURSE GRADE (RESIT) PRF * 0.40 + FCGR*0.60


*** Resit Exam is Not Administered in Institutions Where Resit is not Applicable.

Further Notes About Assessment Methods

None

Assessment Criteria

Learning outcomes, intermediate and long-answer questions will be evaluated with classical written final exam. Strengthened by homework. Midterm exam will consist of half of the evaluation of laboratory applications

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Prof Dr Yasemin Başbınar
yasemin.baskin@deu.edu.tr 0 232 4125890/5801

Office Hours

Monday 12.30-13.30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 15 2 30
Preparations before/after weekly lectures 15 8 120
Final 1 1 1
TOTAL WORKLOAD (hours) 151

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12
LO.155
LO.255
LO.355
LO.455
LO.555
LO.655

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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