COURSE UNIT TITLE

: TRANSLATIONAL PERSPECTIVES IN CANCER

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
TRO 6002 TRANSLATIONAL PERSPECTIVES IN CANCER ELECTIVE 1 0 0 6

Offered By

Translational Oncology

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR DOCTOR YASEMIN BAŞBINAR

Offered to

Adeloscent and Young Adult Oncology PhD
Translational Oncology
Translational Oncology

Course Objective

Course Objective: Developments in basic science "results-oriented" translate to oncology practice. Oncology discipline is evolving from the laboratory bench to the bedside approach in recent years. Discussion of this interface approach will be useful in understanding the development process. The course content; "From the laboratory to the bedside of cancer" overview, risk assessment molecular approaches and individual risk assessment, Translational individualized and targeted treatment approach, overlooking the oncology disease management, Multidisciplinary Council Structure and Operating Principles, Translational Approaches in gynecologic cancer, Head and Neck Cancer, Colorectal Cancer, Lung Cancer,Urogenital Cancer, Breast Cancer issues will be discussed.

Learning Outcomes of the Course Unit

1   1. Knowledgeable about the concept of translational medicine from the bench to the bed.
2   2. Be able to understand the individual risk assessment.
3   3. Be able to know multidisciplinary Cancer Council Structure and Operating
4   4. Be able to recognize and comprehend translational individual, targeted therapies in cancer
5   5. Be able to express the translational approaches in the management of oncologic diseases.
6   6. Be able to design a research on translational cancer management

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 "From the laboratory to the bedside of cancer" Overview
2 Molecular approach to risk assessment and individual risk assessment 1
3 Molecular approach to risk assessment and individual risk assessment 2
4 Translational approach to individualized and targeted treatment 1
5 Translational approach to individualized and targeted treatment 2
6 Translational approach to individualized and targeted treatment 3
7 Importance of translational approaches to the management of oncological diseases
8 Multidisciplinary Council Structure and Operating Principles
9 Translational approaches in Gynecologic Cancer
10 Translational approaches in Head and Neck Cancer
11 Translational approaches in Colorectal Cancer
12 Translational approaches In Lung Cancer
13 Translational approaches in Urogenital Cancer
14 Translational approaches in Breast Cancer
15 Debate

Recomended or Required Reading

Molecular Biology of the Cell, 6th Edition. Ed. Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter. Garland Publishers
Essential Cell Biology - 4th Edition Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander D Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter Garland Publishers
The Biology of Cancer, 2nd Edition, Robert A. Weinberg, Garland Publishers
Molecular Biology of the Gene, 7th edition, James Watson, Alexander Gann, Tania Baker, Michael Levine, Stephan Bell, Richard Losick, Stephan Harrison Pearson Cold Spring harbor Laboratory Press.
Principles of Molecular Diagnostics and Personalized Cancer Medicine, Dongfeng Tan, henry Lynch, Wolters Kluwer, Lippincott Williams&Wilkins.
The Handbook of Biomarkers, Kewal Jain, Humana Press
Translational and Experimental Clinical Research, Daniel Schuster, William Powers, Lippincott Williams&Wilkins.

Planned Learning Activities and Teaching Methods

Lectures, the topics with classroom activities (presentations and homework assignments) to consolidate and discussion

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 PRF PERFORMANCE
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE MTE * 0.20 +PRF * 0.20 + FIN* 0.60
5 RST RESIT
6 FCGR FINAL COURSE GRADE MTE * 0.20 +PRF * 0.20 +RST* 0.60


*** Resit Exam is Not Administered in Institutions Where Resit is not Applicable.

Further Notes About Assessment Methods

None

Assessment Criteria

1. The learner will clearly define outlined LO1, LO2, LO3, and LO4 which will evaluate with exam.
2. The learner will recognize LO5, LO6 will evaluate with homework, prepared presentations by themselves and exam.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

ender.ellidokuz@deu.edu.tr ; 0 232 412 58 01

Office Hours

ender.ellidokuz@deu.edu.tr ; 0 232 412 58 01

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 15 1 15
Preparations before/after weekly lectures 15 5 75
Preparation for midterm exam 1 8 8
Preparation for final exam 1 10 10
Preparing assignments 5 4 20
Preparing presentations 2 10 20
Final 1 1 1
Midterm 1 1 1
TOTAL WORKLOAD (hours) 150

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12
LO.15555555
LO.25555555
LO.355555555
LO.45555555
LO.555555555555
LO.6555555555555