COURSE UNIT TITLE

: NEUROBIOLOGICAL BASIS OF SCHIZOPHRENIA

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
SBI 5043 NEUROBIOLOGICAL BASIS OF SCHIZOPHRENIA ELECTIVE 2 2 0 9

Offered By

Basic Neuroscience

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR DOCTOR KÖKSAL ALPTEKIN

Offered to

Clinical Neuroscience
Basic Neuroscience

Course Objective

Examining the formation mechanisms of genetic and neurochemical components of psychotic disorders, particularly schizophrenia. In this context, to review the neurochemical basis of behaviour and thought, examination of schizophrenia clinics, particularly behavioural and thought disorders, investigation of cognitive dysfunctions and neurochemical aspects of drugs used in schizophrenia.

Learning Outcomes of the Course Unit

1   To learn genetical and neurochemical components of formation mechanisms of psychotic disorders
2   To learn neurochemical basis of behaviour and thought
3   To learn cognitive dysfunctions of schizophrenia clinic
4   To be informed of neurochemical basis and drug therapies of schizophrenia
5   To have knowledge about genetics of schizophrenia and imaging findings

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Introduction: definition and classification of psychotic disorders
2 Neurobiological Basis of behaviour and thought
3 Clinical properties of schizophrenia and other psychotic disorders
4 Ethiology of schizophrenia: neurodevelopmental disorder
5 MIDTERM The place of dopamine system and other neurotransmitters in ethiology of schizophrenia
6 Cognitive processes: Introduction to neuropsychology
7 Neural cycles and cognitive process
8 Cognitive deficits in schizophrenia
9 Brain imaging findings in schizophrenia
10 Genetics of schizophrenia
11 Pharmacogenetic developments in schizophrenia
12 Description and classification of anti-psychotic drugs
13 Presentations
14 Overview

Recomended or Required Reading

Textbook(s): Comprehensive Care of Schizophrenia (A textbook of clinical management). Ed. Jeffrey A Lieberman, Robin M Murray. Martin Dunitz Ltd., 2001
Supplementary Book(s):
1. Molecular Neurobiology. For the Clinician (Review of Psychaitry Series Vol 22). Ed. Dennis S. Charney.. American Psychiatric Publishing, Inc.Arlington VA, 2003.
2. Essential Psychopharmacology. Neuroscientific basis and practical applications. Stephen M Stahl. Cambridge University Pres, 2000.
3. Schizophrenia Bulletin, Schizophrenia Research, Biological Psychiatry, Arch General Psychiatry, J Clinical Psychiatry, Brain Research, gibi güncel dergiler

Planned Learning Activities and Teaching Methods

Theoretical studies and Tutorial

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 PRF PERFORMANCE
2 FIN FINAL EXAM
3 FCG FINAL COURSE GRADE PRF * 0.40 + FIN*0.60
4 RST RESIT
5 FCGR FINAL COURSE GRADE (RESIT) PRF * 0.40 + FCGR*0.60


*** Resit Exam is Not Administered in Institutions Where Resit is not Applicable.

Further Notes About Assessment Methods

None

Assessment Criteria

Knowledge will be evaluated via exams

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

412 4157

Office Hours

Friday 16.00

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 15 2 30
Tutorials 15 2 30
Preparations before/after weekly lectures 15 5 75
Preparation for midterm exam 1 20 20
Preparation for final exam 1 30 30
Preparing assignments 15 2 30
Preparing presentations 1 7 7
Final 1 2 2
Midterm 1 2 2
TOTAL WORKLOAD (hours) 226

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10
LO.15
LO.253
LO.35
LO.45
LO.545