COURSE UNIT TITLE

: BASIC IMMUNOLOGY

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
MIK 5010 BASIC IMMUNOLOGY ELECTIVE 3 0 0 3

Offered By

Microbiology

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR DOCTOR ABDURRAHMAN HÜSEYIN BASKIN

Offered to

Medical Biology and Genetics
Microbiology
Biochemistry
Basic Oncology
MEDICAL GEOLOGY
Molecular Medicine
Laboratory Medicine
Medical Parasitology
Basic Oncology
Pharmacology
TRANSLATIONAL MEDICINE

Course Objective

The course aims to build an insight about the components of the immune system,
their interactions, immune responses and the regulation at molecular,
cellular and systems levels.

Learning Outcomes of the Course Unit

1   Be able to define the components and stages of immune system
2   Be able to define the cells and functions of immune system.
3   Be able to define the types and properties of immune responses
4   Be able to define the properties of antigens, antigen presenting cells and antigen binding mechanisms
5   Be able to define the innate immune responses.
6   Be able to define the adaptive immune responses

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 General properties of immune system. Innate and adaptive immunity Cellular and humoral immunity
2 Properties of immune respone Stages of immune response
3 Cells of immune system Mononuclear cells, Lymphoid cells
4 Granulocytes (neutrophils, eosinophils and basophiles), Endothelial cells, Cellular surface molecules used for typing of the cells
5 Organs and tissues of immune system. Structures and functions of primary lymphoid tissues (thymus, bone marrow), secondary lymphoid tissues (lymph nodules, spleen) Lymphocyte traffic and adhesion molecules
6 Antigen. What s Antigen, immunogen, epitope Structural properties of antigens
7 Antigen binding. T cell depended and T cell independed antigens. Lectines and super antigens.
8 Antibody. Molecular structure of antibodies (heavy-light chains, constant and variabl domains, isotype, allotype, idiotypical determinants, activation of compleman cascade), Antigen-antibody relations (affinity, avidity, cross reaction)
9 Function of antibodies, opsonisation
10 Antigen binding receptors. Major histocompatibility molecules (MHC), MHC types (MHC I ve II), functions, and role of the MHC molecules in the pathogenesis
11 Complement system. Activation of complement cascade by the classical, alternative and lectine pathways.
12 Inflammation; development of acute inflammation and chronical inflammation.

Recomended or Required Reading

Essential Immunology, Ivan Roitt
2. Cellular and Molecular Immunology, Abul K. Abbas
3. Fundamental Immunology, Paul.

Planned Learning Activities and Teaching Methods

Theoretical lectures and interactive discussions among the students and lecturer.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 FIN FINAL EXAM
3 FCG FINAL COURSE GRADE MTE * 0.50 + FIN* 0.50
4 RST RESIT
5 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.50 + RST* 0.50


*** Resit Exam is Not Administered in Institutions Where Resit is not Applicable.

Further Notes About Assessment Methods

None

Assessment Criteria

All of the learning outcomes and learning objectives are given as lectures and interactive discussion.
Mid-term and final exams being tested all the outputs.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Hüseyin Baskın; Dokuz Eylül University Medical Faculty, Department of Medical Microbiology,
Balçova, Izmir, Turkey. , huseyin.baskin@deu.edu.tr

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 12 4 48
Preparations before/after weekly lectures 4 1 4
Preparation for midterm exam 1 8 8
Preparation for final exam 1 10 10
Midterm 1 3 3
Final 1 3 3
TOTAL WORKLOAD (hours) 76

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9
LO.15
LO.24
LO.35
LO.44
LO.54
LO.65

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

Copyright 2015 DEÜ. BİD

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