COURSE UNIT TITLE

: BASIC CHEMISTRY

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
BIO 5021 BASIC CHEMISTRY ELECTIVE 2 0 0 5

Offered By

Biochemistry

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

ASSOCIATE PROFESSOR NILGÜN YENER

Offered to

Medical Biology and Genetics
Biochemistry

Course Objective

Chemistry is a basic science present in the foundations of various applied scientific fields including medical sciences. The aim of this course is to present the necessary chemical knowledge which would help understanding the biological and biochemical processes.
In order to lead a better understanding of the structures and functions of the biomolecules, the formation of three-dimensional molecular structures will be studied in detail. For this purpose, the topics of molecular structure , mole concept and chemical bonding will be studied comprehensively. In addition apprehension of the functional groups constituting the biomolecules and their properties will be provided. A general classification of chemical reactions participated in biochemical processes will be made along with a discussion about the basic knowledge anticipating their phyisiological bases (properties of the reaction media, temperature, pH and buffer) fundemental to their process. Chemical kinetics and catalysis will be studied in order to make the enzymes which are biological catalysts be understood. Energy is one of the necessities of life. In order to give a better understanding of this concept, the functions of chemical thermodynamics such as intrinsic energy , enthalpy , entropy , and free energy will be studied and be associated with biological processes.

Learning Outcomes of the Course Unit

1   Knowledge is gathered about the subjects constituting the bases of biochemistry
2   The three dimensional molecular models and their isomers are understood
3   Intra or intermolecular bonding properties are apprehended
4   Organic structure and their denominations are learned
5   Functional groups and their classical reactions are apprehended
6   Constitutes of biochemical reaction media (temperature, pH) are comprehended
7   Reaction kinetics and catalysis concepts are comprehended
8   Life and energy concepts are interlinked

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Introduction Elecromagnetic Spectrum and Atomic theory Quantum numbers and Atomic Orbitals Essential Elements and Periodic Table
2 Chemical Bonding Basic Concepts : Ionic and Covalent Bonding An introduction to Valance Bond and Molecular Orbital Theories
3 Noncovalent Bonding and Intermolecular Forces Hydrogen Bonds Ionic Bonds (polar interactions) Van der Waals Bonds Hydrophobic Interactions
4 Organic Compounds and IUPAC Nomenclature Fonctional Groups and General Organic Reactions Aromatic Hydrocarbons
5 SMALL GROUP ACTIVITY
6 Stereochemistry and Chiral Molecules The Biological Significance of Chirality Isomerism : Constituonal Isomers and Stereoisomers Enantiomers and Chiral Molecules Optical Activity SMALL GROUP ACTIVITY
7 Types of Solutions Homogeneous Systems : Molarity, Molality, Normality Heterogeneous Systems : Colloids and Suspensions
8 SMALL GROUP ACTIVITY Concentration Calculations
9 Mid-term EXAM
10 Acids and Bases: A Brief Introduction and Overwiew Self - Ionisation of Water and Concept of pH Hydrolyses, SMALL GROUP ACTIVITY Calculation of pH Buffer Solutions
11 Mid-term Presentations from the students
12 Chemical Kinetics The Rate of a Chemical Reaction Effect of Concentrations on Rates of Reactions Effect of Temperature on Reaction Rates Catalysis
13 Chemical Thermodynamics Spontaneity: Meaning of Spontaneous Change The Concept of Entropy Criteria for Spontaneous Change: The Second Law of Thermodynamics Standard Free Energy
14 Presentations from the Students

Recomended or Required Reading

Main textbooks:
1. General Chemistry - Principles and Modern Aplications , 9th Edition, Ralph Petrucci, William S. Harwood, Geoff E. Herring
2. Genel Kimya Ilkeler ve Modern uygulamalar -Petrucci, Harwood, Herring - 8. Baskıdan Çeviri Editörleri : Tahsin Uyar, Serpil Aksoy 2002, Palme Yayıncılık
Supplementary textbooks:
3. Organik Chemistry. T.W. Graham Solomons, Craig B. Fryhle, 8th Edition, 2004, John Wiley & Sons , USA.
4. Organik Chemistry . A Brief Course. R.C. Atkins, F.A. Carey 3th Edition, 2002 McCraw-Hill Companies, NY

Planned Learning Activities and Teaching Methods

The course will be comprised of a theorethical part along with a case study and group study. These activities are held together. The course will be tought in an interactive manner. The students are expected to attend the lecture having studied the subject utilizing the suggested bibliography.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 PRF PERFORMANCE
3 FIN FINAL EXAM
4 FCGR FINAL COURSE GRADE MTE * 0.30 + PRF* 0.30 + FIN* 0.40
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.30 + PRF* 0.30 + RST* 0.40


*** Resit Exam is Not Administered in Institutions Where Resit is not Applicable.

Further Notes About Assessment Methods

If the instructor needs to add some explanation or further note, this column can be selected from the DEBIS menu.

Assessment Criteria

Optional, if the instructor needs to add some explanation or further note, this column can be selected from the DEBIS menu.

Language of Instruction

Turkish

Course Policies and Rules

The students are expected attend the lecture having studied the subject and if they have an excuse, the lecturer should be informed. In addition, they are expected to contribute actively to discussion and group-work. Attending in at least 70 percent of lectures are mandatory.

Contact Details for the Lecturer(s)

Nilgün Yener
Phone: 412 44 13
GSM: + 533 525 59 96

Office Hours

Mondays 13.30-14.30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 15 2 30
Preparations before/after weekly lectures 15 2 30
Preparation for midterm exam 1 15 15
Preparation for final exam 1 15 15
Preparing assignments 1 15 15
Preparing presentations 1 15 15
Preparation for quiz etc. 1 5 5
TOTAL WORKLOAD (hours) 125

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9
LO.15
LO.24
LO.35
LO.45
LO.54
LO.65
LO.75
LO.85