COURSE UNIT TITLE

: INTRODUCTION TO THE CLINICS- NEOPLASIA

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
KGN 3107 INTRODUCTION TO THE CLINICS- NEOPLASIA COMPULSORY 5 2 0 7

Offered By

Medicine

Level of Course Unit

First Cycle Programmes (Bachelor's Degree)

Course Coordinator

PROFESSOR DOCTOR KUTSAL YÖRÜKOĞLU

Offered to

Medicine

Course Objective

The aim of this block is to 1) learn neoplasia terminology, pathogenesis, molecular mechanisms and main principles of treatment, 2) learn the basics of preclinical anamnesis and physical examination.

Learning Outcomes of the Course Unit

1   Viral oncogenesis
2   Understanding the biological models explaining the carcinogenesis process, genetic basis of cancer, multistep carcinogenesis
3   Differentiation of benign-malignant, solid tumor concept, basic principles in naming, metastasis biology and physiopathology, findings and mechanisms of multisystem involvement.
4   Basic biology of multiple system neoplasia syndromes
5   The concept of lymphadenopathy, physiopathology, classification according to underlying causes
6   Classifying adult and childhood lymphomas, Classifying acute leukemias, Understanding etiopathogenesis
7   Shock types, clinical findings, diagnosis, physiopathology
8   Cancer-related metabolic problems, paraneoplastic syndromes, symptoms of lung, bladder, cervix and breast cancer and social screening methods
9   Hereditary, environmental risk factors, cancer prevention and social screening methods
10   Principles of approach to the terminal patient
11   Understanding the physician's perspective and the patient's perspective
12   Cardiopulmonary resuscitation

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Viral oncogenesis Carcinogenesis models
2 Genetics of cancer Multistep carcinogenesis
3 Neoplasia Pathogenesis of neoplasia
4 Classification of tumors Microenvironment of tumors
5 Physiopathology of metastasis Biology of metastasis
6 multisystem neoplasia syndroms Lymphadenopathy
7 Pathogenesis of lymphoproliferative disorders Adult and childhood lymphomas
8 Pathology of lymphomas Sepsis
9 Nosocomial infections Fever etiology other than infections
10 Definition and types of shock Physiopathology of shock
11 Organ changes of shock Basic principles of hemodynamics and hemodynamic changes in shock
12 Pharmacological properties of sympathomimetic agents used in shock therapy Basic principles of malignancy diagnosis
13 Paraneoplastic syndromes Risk factors in cancer development, prevention and screening methods
14 Surgical treatment principles in malignancies Systemic treatment principles in malignancies
15 Radiation therapy principles in malignancies The mechanism of action of drugs used in cancer treatment
16 Psychosocial aspects of cancer Supportive care approaches in the patient with cancer (nutrition and pain)
17 Physician and patient perspective during systemic history and physical examination

Recomended or Required Reading


1-Tıbbi Mikrobiyoloji, Patrick R Murray, Rosenthal KS, Pfaller MA. (çev. ed) Ahmet C Başustaoğlu, 2010.
2-Cellular and Molecular Immunology, Abbas AK, Lichman AH, Pillai S., 2012.
3-Clinical Diagnosis and Management by Laboratory Methods, Henry JB, 2012.
4-Rasyonel Tedavi Yönünden Tıbbi Farmakoloji, Kayaalp, S.O., 2009
5-Basic& Clinical Pharmacology, Katzung BG, 2007.
6-Pathologic Basis of Disease, Robbins and Cotran, 2010

Planned Learning Activities and Teaching Methods

Problem-based learning sessions
Presentations
Laboratory practice (pathology)
Introduction to the clinic and practice of professional skills

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE 1 MIDTERM EXAM 1
2 MTE 2 MIDTERM EXAM 2
3 MTE 3 MIDTERM EXAM 3
4 MTE 4 MIDTERM EXAM 4
5 MTEG MIDTERM AVERAGE GRADE MTE 1 +MTE 2 + MTE 3+MTE 4 /4
6 FIN FINAL EXAM
7 FCG FINAL COURSE GRADE MTEG *0.4 +FIN * 0.6
8 RST RESIT
9 FCGR FINAL COURSE GRADE (RESIT) MTEG *0.4 +RST * 0.6


*** Resit Exam is Not Administered in Institutions Where Resit is not Applicable.

Further Notes About Assessment Methods

None

Assessment Criteria

In all semesters, success grades are evaluated over 100 (one hundred) full points. Term passing score 65
(sixty five).
Student Achievement Assessment (ÖBD) average must be at least 50 (fifty) points.

Language of Instruction

Turkish

Course Policies and Rules

Will be announced

Contact Details for the Lecturer(s)

Will be announced

Office Hours

Will be announced

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 36 1 36
Tutorials 1 2 2
PBL Session 3 9 27
Basic clinical skills practice 1 2 2
Procedural skills practice 1 2 2
Preparation for block-end exam 1 50 50
Preparation before-after PBL/lectures 5 10 50
Block-end exam 1 3 3
TOTAL WORKLOAD (hours) 172

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12PO.13PO.14
LO.15253333
LO.2523333
LO.35233333
LO.45233333
LO.554353333
LO.652353333
LO.75233333
LO.852443333
LO.95545543333
LO.1055253333
LO.1155253333
LO.1253333333