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Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS MPT 6005 BASıC CONCEPTS IN MOLECULER PATHOLOGY ELECTIVE 3 0 0 9

Offered By

Molecular Pathology

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

ASSOCIATE PROFESSOR BURÇIN PEHLIVANOĞLU

Offered to

Molecular Pathology

Course Objective

To learn the basic concepts about the regulation and defects of cellular processes, gene expression and cell cycle as well as chromosomal abnormalities, gene mutations and epigenetic changes in order to understand and apply at molecular pathology and using correct terminology.

Learning Outcomes of the Course Unit

1   Students will be able to understand the flow of the genetic information flow, mechanisms of gene expression and signal transduction. 2   Students will achieve the basic concepts about the chromosomal structure and abnormalities as well as genetic diseases related to chromosomal abnormalities. 3   Students will be able to understand the types of mutations (point, deletion, insertion, etc.) and apply the terminology. 4   Students will be able to understand the epigenetic changes and their relation with diseases. 5   Students will be able to understand the mechanisms of DNA repair and the relation with diseases.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description 1 Genetic information flow and gene expression I Mechanisms of genetic diseases 2 Genetic information flow and gene expression II DNA damage and repair mechanisms 3 Chromosome Structure Personalized Medicine 4 Gene Mutations Targeted treatment biomarkers 5 Terminology for mutations 6 Mutations and development of diseases 7 Epigenetic changes 8 Epigenetic changes and development of diseases 9 Cellular signal transduction mechanisms 10 Signal transmission mechanisms and development of diseases

Recomended or Required Reading

To be announced.

Planned Learning Activities and Teaching Methods

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA 1 ASG ASSIGNMENT 2 PAR PARTICIPATION 3 FCG FINAL COURSE GRADE 4 FCG FINAL COURSE GRADE ODV * 0.30 + DKL * 0.20 + FN* 0.50 5 RST RESIT 6 FCGR FINAL COURSE GRADE (RESIT) ODV * 0.30 + DKL * 0.20 + BUT* 0.50 *** Resit Exam is Not Administered in Institutions Where Resit is not Applicable.

Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Ass. Prof Dr Mehtat Ünlü Dokuz Eylül University Faculty of Medicine Deppartment of Pathology Inciralti/Balçova Izmir mehtat.unlu@deu.edu.tr

Office Hours

Friday 13:00-15:00

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours) Lectures 15 3 45 Student Presentations 1 25 25 Preparations before/after weekly lectures 15 2 30 Preparing assignments 1 60 60 Preparation for final exam 1 60 60 Final 1 5 5 TOTAL WORKLOAD (hours) 225

Contribution of Learning Outcomes to Programme Outcomes

PO/LO PO.1 PO.2 PO.3 PO.4 PO.5 PO.6 PO.7 PO.8 PO.9 PO.10 PO.11 LO.1 5 5 4 4 3 LO.2 5 5 4 4 3 LO.3 5 5 4 4 3 LO.4 5 5 4 4 3 LO.5 5 5 4 4 3