COURSE UNIT TITLE

: PROTEIN BIOCHEMISTRY AND BIOTECHNOLOGY

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
MBG 5023 PROTEIN BIOCHEMISTRY AND BIOTECHNOLOGY ELECTIVE 3 0 0 9

Offered By

Molecular Biology and Genetics

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

ASSOCIATE PROFESSOR HASAN BUĞRA ÇOBAN

Offered to

Molecular Biology and Genetics
Biomedicine and Health Technologies
Molecular Biology and Genetics

Course Objective

Proteins, which are one of the important macromolecules for organisms, are used in many fields including medical, pharmacological, food and analytical industries. The structure, engineering, sources and production, purification and characterization of proteins will be discussed within the context of this course. Also, proteins used for therapeutical, analytical purposes and industrial purposes will be evaluated.

Learning Outcomes of the Course Unit

1   Understand three dimensional structure, folding mechanisms, post translational modifications and functions of proteins, and enzyme kinetics.
2   Have knowledge about proteomics and protein engineering.
3   Have knowledge about protein sources, engineering, production, purification and characterization method(s) for the application fields of protein biotechnology.
4   Evaluate the biotechnological importance of proteins in therapeutical, industrial, analytical fields of biotechnology.
5   Determine proper source, production, purification and characterization method(s) of proteins.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Introduction to proteins and proteomics
2 Protein structure and enyzme kinetics
3 Protein sources in biotechnology
4 Protein engineering
5 Protein purification and characterization
6 Hormons, interleukins and vaccines
7 Enzymes and antibodies
8 Midterm
9 Biological, physical, and chemical factors in industrial protein productions
10 Bioreactor types used in biological protein productions
11 Calculation of cellular growth kinetic and parameters in biological protein productions
12 Biological protein productions in batch, fed-batch, and continuous bioreactor systems
13 Separation and purification methods in protein production industry
14 Case studies about protein production and discussion
15 Example problems, solutions, discussion
16 Final exam

Recomended or Required Reading

Gary Walsh. Proteins: Biochemistry and Biotechnology, 2nd Edition, Wiley, 2014.
Michael L. Shuler, Fikret Kargi. Bioprocess Engineering Basic Concepts, 2ndEdition, Prentice Hall, 2002.

Planned Learning Activities and Teaching Methods

1. Presentation
2. Interactive narrative
3. Question-answer technique
4. Homework

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 FIN FINAL EXAM
3 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.50 + FIN *0.50
4 RST RESIT
5 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.50 + RST * 0.50


*** Resit Exam is Not Administered in Institutions Where Resit is not Applicable.

Further Notes About Assessment Methods

None

Assessment Criteria

Evaluation will be performed based on presentations, participation to the course, sharing opinion during discussion sections, midterm and final exams.

Language of Instruction

English

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

bugra.coban@deu.edu.tr

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 15 3 45
Preparation for midterm exam 1 20 20
Preparation for final exam 1 25 25
Preparing assignments 1 20 20
Preparation for quiz etc. 1 20 20
Preparations before/after weekly lectures 15 6 90
Midterm 1 2 2
Final 1 2 2
TOTAL WORKLOAD (hours) 224

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8
LO.15
LO.25
LO.35
LO.45
LO.55

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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