COURSE UNIT TITLE

: TISSUE REPAIR AND REGENERATION

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
MBG 5032 TISSUE REPAIR AND REGENERATION ELECTIVE 3 0 0 9

Offered By

Molecular Biology and Genetics

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR DOCTOR ŞERIFE ESRA ERDAL BAĞRIYANIK

Offered to

Molecular Biology and Genetics
Molecular Biology and Genetics

Course Objective

To learn the fundamental ways cells respond to injury
To explore the differences in mechanisms of regeneration in various tissues and organs
To understand how and why different organisms respond to injury differently
To discuss strategies on how to repair, replace and regenerate various tissues and organs to solve major clinical problems
To learn the potentials of stem cells in curative therapy approaches

Learning Outcomes of the Course Unit

1   To understand the fundamental concepts and the basic strategies of repair and regeneration in response to injury in various tissues and organs
2   To distinguish the different mechanisms of regeneration
3   To understand the regenerative capacities of different models
4   To understand the concept and importance of stem cells in regeneration
5   To appreciate the potential of stem cells in regenerative medicine
6   To acquire the ability to access, present and discuss the knowledge on tissue repair and regeneration

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Introduction to general mechanisms of regeneration
2 Introduction to the concept and types of stem cells
3 Wound healing response
4 Wound closure mechanisms
5 Regeneration models: planarians
6 Regeneration models: invertebrates
7 Regeneration models: amphibians
8 Regeneration models: amphibians
9 Mid-term exam
10 Regeneration models: zebrafish
11 Regeneration models: zebrafish
12 Regenerative capacities of mammals
13 Regenerative capacities of mammals
14 The potential of stem cells in therapy approaches
15 Gene therapy approaches
16 Final exam

Recomended or Required Reading

Textbook(s): Developmental Biology, 10. Edition. Scott F. Gilbert
Online version: http://10e.devbio.com/
Additional book information will be announced later.
Supplementary Book(s):
References: Helpful reviews on the topics will be shared with students.

Planned Learning Activities and Teaching Methods

1. PowerPoint lecture presentations: Lecture subjects will be covered as PowerPoint presentations schematized and simplified for easy visual comprehension.
2. Research article presentation assignment: Students will choose recent research articles about essential or current repair and regeneration related topics, present the key points of the article as a short presentation and discuss those with the audience. All presentations will be held together on a predetermined date outside of lecture hours.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 FIN FINAL EXAM
3 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.50 + FIN *0.50
4 RST RESIT
5 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.50 + RST * 0.50


*** Resit Exam is Not Administered in Institutions Where Resit is not Applicable.

Further Notes About Assessment Methods

An interactive participation of students is expected during the lectures.

Assessment Criteria

Mid-term and final exams: A high percentage (70%) of correct answers, showing that the lecture topics are well digested, is expected.
Oral presentation: The student is expected to understand and present a selected paper, state how well the paper sets forth the scientific question and put forward an idea on future perspectives.

Language of Instruction

English

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Tel: 0232-299 41 56
E-mail: gunes.ozhan@deu.edu.tr

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 3 42
Preparations before/after weekly lectures 14 5 70
Preparation for midterm exam 1 30 30
Preparation for final exam 1 30 30
Preparing presentations 1 30 30
Final 1 10 10
Midterm 1 10 10
TOTAL WORKLOAD (hours) 222

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8
LO.14
LO.22
LO.32
LO.43
LO.53
LO.63