COURSE UNIT TITLE

: GENETICS AND GENOMICS

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
MBG 5022 GENETICS AND GENOMICS ELECTIVE 3 0 0 9

Offered By

Molecular Biology and Genetics

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

ASSISTANT PROFESSOR YAVUZ OKTAY

Offered to

Molecular Biology and Genetics
Molecular Biology and Genetics

Course Objective

To have a solid understanding of the principles of genetics and a broad knowledge of all aspects of genomics.

Learning Outcomes of the Course Unit

1   to explain the structural and functional organization of the prokaryotic and eukaryotic genomes
2   to predict the genotypic and phenotypic ratios for genetics crosses
3   to discuss the mechanisms of DNA replication, recombination, transcription and translation and how mutations can alter the outcomes of these processes
4   to explain the use of comparative genomics in research settings
5   to discuss the ethical and legal issues associated with study and genetic/genomic analysis of human diseases
6   To describe the principles of various Next Generation Sequencing technologies
7   To explain the use of array-based technologies in the clinic and research settings
8   To discuss the principles of proteomics based approaches
9   To have a broad understanding of the methods and approaches used in systems biology
10   to present research findings in an effective manner

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Mendelian Genetics
2 Population and non-Mendelian Genetics
3 Genomes of Prokaryotes and Eukarytotes
4 Comparative Genomics
5 Evolution and Genomic Change
6 DNA Replication
7 DNA Repair Mechanisms
8 Principles of Gene Regulation and Epigenetics I
9 MIDTERM
10 Principles of Gene Regulation and Epigenetics - II
11 Genomics and Human Biology
12 Next Generation Sequencing Technologies
13 Microarrays and Transcriptomics
14 Proteomics and Systems Biology
15 Assignment Presentations
16 Final Exam

Recomended or Required Reading

Textbook(s): Introduction to Genomics, 2nd edition by Arthur M. Lesk. Oxford University Press; 2012.
ISBN-10: 0199564353
Genetics: From Genes to Genomes, 5th edition by Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro. McGraw-Hill Education; 2014
ISBN-10: 0073525316

Supplementary Book(s): Genomics: Essential Methods, Edited by Mike Starkey and Ramnath Elaswarapu, Wiley Press, 2010
ISBN: 9780470711576

References:
Materials:

Planned Learning Activities and Teaching Methods

Theoretical lecture with PowerPoint, literature review/discussion, and assignment presentations by students

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 ASG ASSIGNMENT
2 MTE MIDTERM EXAM
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE ASG * 0.30 + MTE * 0.30 + FIN * 0.40
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) ASG * 0.30 + MTE * 0.30 + RST * 0.40


*** Resit Exam is Not Administered in Institutions Where Resit is not Applicable.

Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

English

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Yavuz.oktay@deu.edu.tr

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 15 3 45
Tutorials 15 1 15
Preparations before/after weekly lectures 15 3 45
Preparation for midterm exam 1 25 25
Preparation for final exam 1 30 30
Preparation for quiz etc. 2 10 20
Preparing assignments 1 20 20
Preparing assignments 1 6 6
Final 1 2 2
Midterm 1 2 2
TOTAL WORKLOAD (hours) 210

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8
LO.14
LO.232
LO.33
LO.42
LO.52
LO.62
LO.73
LO.82
LO.93
LO.103

CONTACT INFORMATION
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Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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