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Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS MBG 6109 ADVANCED IMMUNOLOGY ELECTIVE 3 0 0 12

Offered By

Molecular Biology and Genetics

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

ASSOCIATE PROFESSOR DUYGU SAĞ

Offered to

Molecular Biology and Genetics Molecular Biology and Genetics

Course Objective

This course will outline the intricate interplay of various elements of the immune system by the in depth view into several immune responses including infections.

Learning Outcomes of the Course Unit

1   understand the characteristics of the initiation and termination of immune responses 2   understand the molecular basis by which the immune system identifies pathogens 3   understand the mechanisms by which the immune systems combats infections 4   understand and discuss how the interaction of various arms of the immune system is shaped by the challenge at hand 5   understand how pathogens undermine the immune system 6   understand how the immune response can `fail and aspects of therapeutic interventions 7   understand and discuss the elements and challenges of self/non-self discrimination 8   explore and discuss the clinical aspects of immunology through discussions of case studies

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description 1 Self/Non-self discrimination and the world of danger 2 Innate mechanism of pathogen recognition 3 Effector Mechanisms of the innate immune system against pathogens 4 Pathogen recognition by the adaptive immune system 5 Effector Mechanisms of the adaptive immune system against pathogens 6 T Cell Activation and co-stimulation 7 Midterm exam 8 Pathogens and their challenges on the immune system 9 Viral infections 10 Intracellular bacterial Infections 11 Extracellular bacterial Infections 12 Viral and bacterial escape mechanisms of host immunity 13 Responses to Protein Antigens; and mucosal immunity 14 Protozoa Infections 15 Infectious Disease and Vaccines; and experimental systems 16 Final exam

Recomended or Required Reading

Abul Abbas (Ed): Cellular and Molecular Immunology, 8th edition (2014)

Planned Learning Activities and Teaching Methods

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA 1 ASG ASSIGNMENT 2 MTE MIDTERM EXAM 3 FIN FINAL EXAM 4 FCG FINAL COURSE GRADE ASG * 0.30 + MTE * 0.30 + FIN * 0.40 5 RST RESIT 6 FCGR FINAL COURSE GRADE (RESIT) ASG * 0.30 + MTE * 0.30 + RST * 0.40 *** Resit Exam is Not Administered in Institutions Where Resit is not Applicable.

Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

English

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

To be announced.

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours) Lectures 14 3 42 Preparations before/after weekly lectures 14 7 98 Preparation for midterm exam 1 28 28 Preparation for final exam 1 35 35 Preparing assignments 3 9 27 Preparing assignments 1 11 11 Preparing presentations 1 20 20 Design Project 1 30 30 Final 1 5 5 Midterm 1 5 5 TOTAL WORKLOAD (hours) 301

Contribution of Learning Outcomes to Programme Outcomes

PO/LO PO.1 PO.2 PO.3 PO.4 PO.5 PO.6 PO.7 PO.8 LO.1 3 LO.2 3 LO.3 3 LO.4 3 LO.5 2 LO.6 2 LO.7 2 LO.8 2