COURSE UNIT TITLE

: TRANSLATIONAL ONCOLOGY

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
TRO 6016 TRANSLATIONAL ONCOLOGY ELECTIVE 2 0 0 6

Offered By

Translational Oncology

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR DOCTOR YASEMIN BAŞBINAR

Offered to

Translational Oncology
Translational Oncology

Course Objective

The purpose of this course is to promote translational medicine and results-oriented approach. Understand the importance of bed to bench, bench to bed concepts to provide knowledge about.

Learning Outcomes of the Course Unit

1   Knowledgeable about the concept of translational medicine
2   Be able to know what is going on oncology drug development strategies.
3   Be able to critically evaluate the published literature in the field of the translational methods in cancer.
4   Be able to know research models of bed to bench
5   Be able to understand the importance of translational approaches in the field of Oncology

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 "Cancer: From bench to bed" overview
2 Molecular approach in risk assessment and individual risk assessment
3 Biomarker concept in cancer
4 Canceromics, disease management and clinical studies
5 Biomarker studies in early detection and prognosis of cancer
6 Defining therapeutic goals
7 Prediction of chemotherapeutic resistance in cancer
8 Molecular approaches in tumor imaging
9 DNA damage repair and predictive radiotherapy for cancer
10 Research models from cancer biology to cancer clinic
11 Pharmaco-Geno-Proteo-Metabolomics and translational research in cancer
12 Design and implementing pharmacogenomics study in cancer
13 Use of biotechnological developments in cancer clinic
14 Drug development strategies in oncology
15 Recent advances in translational oncology

Recomended or Required Reading

Song, Erwei, Hu, Hai. Translational Research in Breast Cancer. Biomarker Diagnosis, Targeted Therapies and Approaches to Precision Medicine. 2017. Elsevier
Ruiz-Garcia, Erika, Astudillo-de la Vega, H. Translational Research and Onco-Omics Applications in the Era of Cancer Personal Genomics. 2019 Springer.
Ammad Ahmad Farooqi, Muhammad Ismail. Molecular Oncology: Underlying Mechanisms and Translational Advancements.
Clinical and Translational Oncology, springer journal.
Translational Medicine and Drug Discovery, Edited by Bruce H. Littman; 2011 Cambridge University Press
Translational Oncology: Current Clinical Issues & Future Trends, Leonidas C. Platanias, Pedro Gascón Vilaplana, Medical Trends, 2008
Materials: Society for Translational Oncology; : http://www.sto-online.org

Planned Learning Activities and Teaching Methods

Theoretical Lectures, the topics in-class activities (presentations and assignments) to consolidate and discussion and homeworks

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 PRF PERFORMANCE
2 FIN FINAL EXAM
3 FCG FINAL COURSE GRADE PRF * 0.40 + FIN*0.60
4 RST RESIT
5 FCGR FINAL COURSE GRADE (RESIT) PRF * 0.40 + FCGR*0.60


*** Resit Exam is Not Administered in Institutions Where Resit is not Applicable.

Further Notes About Assessment Methods

None

Assessment Criteria

Learning outcomes, intermediate and long-answer questions will be evaluated with classical written final exam. Strengthened by homework

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Prof Dr Yasemin Başbınar
yasemin.baskin@deu.edu.tr 0 232 4125890/5801

Office Hours

Monday 12.30-13.30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 15 2 30
Preparations before/after weekly lectures 15 8 120
Final 1 1 1
TOTAL WORKLOAD (hours) 151

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12
LO.155555
LO.255555
LO.355555
LO.455555
LO.555555