COURSE UNIT TITLE

Offered By

Translational Oncology

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR DOCTOR YASEMIN BAŞBINAR

Offered to

Translational Oncology
Translational Oncology

Course Objective

Translational perspective (from the bed to the lab from the lab to the bed) in cancer, research methods in Preventive Oncology (individuals cancer risk, screening programs and testing; environmental carcinogenesis, Nutrigenomics, population genetics concepts), research methods in Basic Oncology (the diagnostic laboratory techniques; tumor markers), research methods in Clinical Oncology (treatment response, tumor models (in vivo (experimental animals) in vitro (tissue culture), ex vivo models)
advanced molecular methods (hybridization, FISH, flow cytometry, genomics, proteomics, metabolamik, systems biology,molecular cloning, DNA sequencing) in cancer research, treatment technologies (recombinant protein technology,nanobiotechnology, drug design, pharmacogenomics studies, cancer vaccines, cellular modulations) will be discussed.

Learning Outcomes of the Course Unit

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Recomended or Required Reading

Turner, J. Rick. New Drug Development. An Introduction to Clinical Trials: Second Edition. 2010. Springer
Poduri, Ramarao. Drug Discovery and Development: From Targets and Molecules to Medicines. 2021. Springer
Benjamin Blass. Basic Principles of Drug Discovery and Development. 1st Edition. 2015. Academic Press
Ahlbrandt J, Lablans M, Glocker K, Stahl-Toyota S, Maier-Hein K, Maier-Hein L, Ückert F. Modern Information Technology for Cancer Research: What's in IT for Me An Overview of Technologies and Approaches. Oncology. 2020;98(6):363-369. doi: 10.1159/000493638. Epub 2018 Nov 15. PMID: 30439700.
Molecular Biology of the Cell, 6th Edition. Ed. Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter. Garland Publishers
Essential Cell Biology - 4th Edition Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander D Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter Garland Publishers
The Biology of Cancer, 2nd Edition, Robert A. Weinberg, Garland Publishers
Molecular Biology of the Gene, 7th edition, James Watson, Alexander Gann, Tania Baker, Michael Levine, Stephan Bell, Richard Losick, Stephan Harrison Pearson Cold Spring harbor Laboratory Press.
Principles of Molecular Diagnostics and Personalized Cancer Medicine, Dongfeng Tan, henry Lynch, Wolters Kluwer, Lippincott Williams&Wilkins.
The Handbook of Biomarkers, Kewal Jain, Humana Press
Translational and Experimental Clinical Research, Daniel Schuster, William Powers, Lippincott Williams&Wilkins.
Klinik Araştırmalar Kitabı 2014, Hamdi Akan, Hilal Ilbars, Nurşah Çetinkaya, Bilimsel Tıp Yayınevi
Designing Clinical Research 4th Edition, Steven R Cummings , Warren S Browner , Deborah G Grady , Thomas B Newman , Dr Stephen B Hulley, Lippincott Williams&Wilkins.
Journals
Clinical & translational oncology (1699-048X) in Springer
Translational oncology (1944-7124) in PubMed

Planned Learning Activities and Teaching Methods

Lectures, the topics with classroom activities (presentations and homework assignments) to consolidate and discussion

Assessment Methods

Further Notes About Assessment Methods

None

Assessment Criteria

1. The learner will clearly define outlined LO1, LO2, LO4, LO5 and which will evaluate with exam.
2. The learner will recognize LO3, LO6 will evaluate with homework, prepared presentations by themselves and exam.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

gizem.calibasi@deu.edu.tr; 0 232 412 58 01

Office Hours

Thursday11:00-12:00

Work Placement(s)

None

Workload Calculation

Contribution of Learning Outcomes to Programme Outcomes