COURSE UNIT TITLE

: ESSENTIAL GENETICS

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
TRT 5001 ESSENTIAL GENETICS COMPULSORY 2 0 0 4

Offered By

TRANSLATIONAL MEDICINE

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

Offered to

TRANSLATIONAL MEDICINE

Course Objective

This course will enable students to understand main genetic principles and their applications in translational medicine.

Learning Outcomes of the Course Unit

1   to know cell division (mitosis, meiosis) and gametogenesis
2   to know principles of Mendelian genetics and phenotype-genotype relationship
3   to know Mendelian and non-Mendelian inheritance patterns, and comments on pedigrees
4   to know mutation types
5   to describe genotype-phenotype relationship and inheritance mechanism of a single gene disorder
6   to describe genotype-phenotype relationship and inheritance mechanism of a single gene disorder
7   to know basic genetic mechanism of carsinogenesis
8   to know basic principles of population genetics and evolution

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Introduction
2 Cell ciycle, mitosis and meiosis
3 Mutation types
4 Formal genetics
5 Mendelian inheritance I
6 Mendelian inheritance II
7 Mid-term exam
8 Non-Mendelian inheritance I
9 Non-Mendelian inheritance II
10 Population genetics and evolution
11 Single gene disorders
12 Chromosomal aberrations I
13 Chromosomal aberrations II
14 Genetic mechanism of canser

Recomended or Required Reading

Textbook(s):
Klug WM, Cummings MR: Concepts Altıncı baskıdan Çeviri, Palme, 2002
- Griffiths AJF, Miller JH, Suzuki DT, Lewontin RC, Gelbart WM: An Introduction to Genetic Analysis Seventh ed., Freeman, 2000
- Griffiths AJF, Miller JH, Lewontin RC, Gelbart WM: Modern Genetic Analysis Second ed., Freeman, 2002
- Nussbaum RL, McInnes RR, Willard HF: Thompson & Thompson Genetics in Medicine Sixth ed., Saunders, 2001
- Nussbaum RL, McInnes RR, Willard HF: Thompson & Thompson Tıbbi Genetik Altıncı baskıdan Çeviri., Güneş Kitabevi, 2005
Hartl DL, Jones EW: Essetial Genetics a Genomics Perspective Third ed., Jones and Bartlett, 2002
Connor M, Ferguson-Smith M: "Essential Medical Genetics" Fifth ed., Blackwell Science, 1997
Gelehrter TD, Collins FS, Ginsburg D:" Principles of Medical genetics" Second ed., Williams & Wilkins, 1998
Gardner EJ, Simmons MJ, Snustad DP: "Principles of Genetics" Eighth ed., Wiley, 1991

Planned Learning Activities and Teaching Methods

Lectures: Basic theoretical concepts will be explained during lectures
Homework: Students will solve to problem based questions about the previous lecture that are given by the course coordinator, and shall be submitted in writing.
Homework Assignments/Presentation: Each student prepare a presentation as his/her choice for a single gene disease.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 ASG ASSIGNMENT
3 FIN FINAL EXAM
4 FCGR FINAL COURSE GRADE MTE * 0.30 + ASG * 0.20 + FIN* 0.50
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.30 + ASG * 0.20 + RST* 0.50


*** Resit Exam is Not Administered in Institutions Where Resit is not Applicable.

Further Notes About Assessment Methods

None

Assessment Criteria

LO: Will be assessed by a written mid-term exam, final exam and homework.
LO: Will be assessed through listen to the presentation prepared by the students and to ask questions about the presentation in final exam .

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Tel: 412 7 E-posta: cigdem.eresen@deu.edu.tr

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 2 28
Preparations before/after weekly lectures 14 1 14
Preparation for midterm exam 1 10 10
Preparation for final exam 1 12 12
Preparing assignments 10 1 10
Preparing presentations 1 20 20
Final 1 3 3
Midterm 1 3 3
TOTAL WORKLOAD (hours) 100

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9
LO.154
LO.24434
LO.345434
LO.454
LO.544443
LO.644
LO.734343
LO.843343

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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