COURSE UNIT TITLE

: MECHANISM OF LOCALISATION OF RADIOPHARMACEUTICALS

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
RDF 5008 MECHANISM OF LOCALISATION OF RADIOPHARMACEUTICALS COMPULSORY 2 0 0 5

Offered By

Radiopharmaceutical Sciences

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR DOCTOR GAMZE ÇAPA KAYA

Offered to

Radiopharmaceutical Sciences

Course Objective

Aims of this course are to teach mechanism of localization and biodistribution of radiopharmaceuticals

Learning Outcomes of the Course Unit

1   Mechanism of localisation of radiopharmaceuticals
2   Boidistribution of radiopharmaceuticals
3   Excretion of radiopharmaceuticals
4   Metabolism of radiopharmaceuticals

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Introduction to localisation and biodistribution of radiopharmaceuticals on body
2 Spesific ve nonspesific substratlar
3 Capillary Blockade
4 Cell Sequestration
5 Compartmental Localization
6 Active Transport
7 Passive Diffusion
8 Chemisorption (Physicochemical Adsorption)
9 MID-TERM EXAM
10 Exchange Diffusion
11 Antigen/Antibody Reaction
12 Receptor Binding
13 Enzyme substrats
14 Metabolic Trapping
15 FINAL EXAM

Recomended or Required Reading

Textbook(s)/References/Materials:
Main Reference: presentations , Fundamentals of Radiopharmacy, G. Saha,
Auxiliary references:
Radiopharmaceuticals in Nuclear Medicine Practice, R.J.Kowalsky,
Nuclear Medicine Technology and Technics, D.R.Bernier,
Operational Guidance on Hospital Radiopharmacy, IAEA.Atoms,

Planned Learning Activities and Teaching Methods

1. Lecturing
2. Question-Answer
3. Discussion
4. Homework

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 ASG ASSIGNMENT
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE MTE * 0.30 + ODV * 0.40 + FIN* 0.30
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.30 + ODV * 0.40 + RST* 0.30


*** Resit Exam is Not Administered in Institutions Where Resit is not Applicable.

Further Notes About Assessment Methods

None

Assessment Criteria

1. The homeworks will be assessed by directly adding to the mid-term scores.
2. Final examination will be evaluated by assay or test type examination technique

Language of Instruction

Turkish

Course Policies and Rules

1. It is obligated to attend to lessons .
2. The instructor has right to make practical quizzes. The scores obtained from quizzes will be directly added to exam scores.

Contact Details for the Lecturer(s)

gamze.capa@deu.edu.tr

Office Hours

Friday between 10:00-12:00 a.m.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 2 28
Preparations before/after weekly lectures 14 2 28
Preparation for final exam 1 12 12
Preparation for midterm exam 1 12 12
Preparing presentations 1 15 15
Preparing assignments 1 15 15
Final 1 2 2
Midterm 1 2 2
TOTAL WORKLOAD (hours) 114

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12PO.13PO.14PO.15PO.16
LO.15
LO.25
LO.35
LO.45