COURSE UNIT TITLE

: LABORATORY ANIMAL PHARMACOLOGY

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
LHB 6035 LABORATORY ANIMAL PHARMACOLOGY ELECTIVE 1 0 0 3

Offered By

Laboratory Animal Science

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR DOCTOR MEHMET ENSARI GÜNELI

Offered to

Laboratory Animal Science

Course Objective

By this course it is aimed to gain the students information and skills about pharmacology in researches and applications about experimental animals

Learning Outcomes of the Course Unit

1   To be able to define basic concepts about pharmacology
2   To be able to indicate main aspects of basic pharmacokinetic and pharmacodinamic characteristics of drugs
3   To be able to be aware of effects on different systems of drugs used in pharmacology
4   To be able to understand interspecies differences in pharmacology
5   To be able to explain research methods used in pharmacology
6   To be able to do drug applications in experimental animal studies.
7   To be able to do basic laboratory applications which are used in pharmacology
8   To be able to exchange information about drugs

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Defining characteristics of drugs
2 Defining entrance ways of drugs to the organisms, its distribution and its elimination
3 Drug effect Mechanisms
4 Recognition of drug receptors and ligands
5 Drug interactions
6 Factors that change drug interactions
7 Toxic effect of drugs and basic concepts of toxicology
8 Basic laboratory applications and calculations that are used in pharmacology
9 MID-TERM EXAM
10 Defining effects of drugs used in pharmacology, on different systems-1
11 Defining effects of drugs used in pharmacology, on different systems-2
12 Defining effects of drugs used in pharmacology, on different systems-3
13 Interspecies differences and calculations in pharmacology
14 Basic principles of drug application in experimental animals
15 Basic research methods and techniques in pharmacology
16 Homework presentations
17 Homework
18 FINAL EXAM

Recomended or Required Reading

Foreign references:
Drug Dosage in Laboratory Animals: A Handbook. REltherington. E. Borchard, C. D. Barnes, L. G. 1989. West Caldwell, N.J.: Telford Press.
Handbook of Veterinary Drugs: A Compendium for Research and Clinical Use. I.S. Rossoff, 1975. New York: Springer Publishing. 752 pp.
Laboratory Guide in Experimental Pharmacology, Edmunds C, 2010.
Handbook of Experimental Pharmacology, Hofmann, FB, 2004
Laboratory Animal Medicine, James G . Fox, Bennett. J. Cohen, Franklin M. Loew : Academıc Press, Inc. 1984.
Canadian Council on Animal Care, Gulde to the Care and Use of Experimental Animals ; Volume 1.1105-151 Slater street, Ottawa, Ontario KIP 5HP3.,1984
Canadian council on Animal Care, Guide to the Care Use of Experimental Animals ; Volume 2. 1105-151 Slater street, Ottawa, Ontario KIP 5HP3.,1984
Patrick F.Sharp. Marie C.La Regina, : The Laboratory Rat, CRC Press London 1998
Harkness, J.E.; Wagner, J.E. 195 The Biology and Medicine of Rabbits and Rodents, Williams & Wilkins, Ballemira
Wagner J.E.; Manning P.S.; The Blology of the Gulnea Pig, Academic Press 1976666, New York, Lonnnnndon
Mark A. Suckow, Fred A. Douglas. The Laboratory Rabbit CRC Press, 1997
Hedrich Hans (Editor), The Laboratory Mouse (Handbook of Experimental Animals) [Hardcover] 2004.
Guide for the Care and Use of Laboratory Animals Institute of Laboratory Animal Resources Commission on Life Sciences National Research Council National Academy Press Washington, D.C. 1996
Local references:
Kaya S, Veteriner Farmakoloji Medisan Yayıncılık, Ankara, 2007.
Kayaalp SO, Rasyonel Tedavi Yönünden Tıbbi Farmakoloji, Ankara, Pelikan Yayınları, 2009
Süzer Ö, Tedavinin Farmakolojik Temeli (Goodman and Gilman's Çeviri), Istanbul, 2009
Ide T, Laboratuvar hayvanları biliminin temel ilkeleri, Ankara, Medipress Yayıncılık, 2003.
Poyraz Ö, Laboratuar hayvanları bilimi, Ankara, Kardelen ofset baskısı, 2000.
Başaran A, Deney hayvanları; laboratuar teknikleri, Nisan kitabevi yayınları

Planned Learning Activities and Teaching Methods

The strategies were given in Assessment Methods and Work Load Calculation sections

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 ASG ASSIGNMENT
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE MTE * 0.40 +ASG * 0.20 + FIN* 0.40
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.40 +ASG * 0.20 + RST* 0.40


*** Resit Exam is Not Administered in Institutions Where Resit is not Applicable.

Further Notes About Assessment Methods

None

Assessment Criteria

1. Preparing Individual Assignments and presentation
2. Mid-term exam and final exam

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Prof. Dr. Ensari Guneli ensari.guneli@deu.edu.tr

Office Hours

Friday : 12.30 13.30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 5 3 15
Preparations before/after weekly lectures 5 8 40
Preparation for midterm exam 1 5 5
Preparation for final exam 1 5 5
Preparation for quiz etc. 1 2 2
Preparing assignments 1 6 6
Preparing presentations 1 6 6
Final 1 3 3
Midterm 1 3 3
Quiz etc. 1 1 1
TOTAL WORKLOAD (hours) 86

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12
LO.1454
LO.2555
LO.3444
LO.45455444
LO.555
LO.653553455
LO.753553455
LO.85555555

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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