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Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS SBI 6057 NONCODING RNA AND BRAIN ELECTIVE 4 0 0 12

Offered By

Basic Neuroscience

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR DOCTOR ŞERMIN GENÇ

Offered to

Basic Neuroscience

Course Objective

In this course, it is aimed to discuss the in vitro, in vivo and in situ properties of noncoding RNAs in brain in both physiological and pathological conditions.

Learning Outcomes of the Course Unit

1   Getting knowledge of general properties of noncoding RNAs 2   Learning the roles of noncoding RNAs in brain 3   Learning their roles in diagnosis and treatment of neurodegenerative diseases 4   Accessing and analysing scientific knowledge 5   Having the ability of oral and written presentation

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description 1 Nomenclature of noncoding RNAs History Noncoding RNA databases-1 Noncoding RNA databases-2 Long noncoding RNAs Role of Long noncoding RNAs in brain Group study (article discussion) 2 Exogenous siRNAs Endogenous siRNAs Roles of siRNAs in brain Introduction to miRNAs miRNA genes miRNA biogenesis Group study (article discussion) 3 Functions of miRNAs miRNA detection methods miRNA targets Expression of miRNAs in brain Function of miRNAs in brain development miRNA and neurodegenerative diseases Group study (article discussion) 4 miRNA and stroke Neuroimmunological diseases and miRNA miRNAs in diagnosis of neurodegenerative diseases miRNAs in treatment of neurodegenerative diseases Student presentations Group study (article discussion)

Recomended or Required Reading

Textbook(s): SCI articles related to topics

Planned Learning Activities and Teaching Methods

Oral presentation, literature search

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA 1 MTE MIDTERM EXAM 2 FIN FINAL EXAM 3 FCG FINAL COURSE GRADE MTE * 0.40 + FIN* 0.60 4 RST RESIT 5 FCGR FINAL COURSE GRADE MTE * 0.40 + RST* 0.60 *** Resit Exam is Not Administered in Institutions Where Resit is not Applicable.

Further Notes About Assessment Methods

None

Assessment Criteria

The knowledge will be evaluated by exams, ability of obtaining information by scanning literature and estimating the obtained information will be evaluated by homework.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

23595

Office Hours

Friday 16-17

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours) Lectures 60 1 60 Preparations before/after weekly lectures 60 2 120 Preparation for midterm exam 1 30 30 Preparation for final exam 1 36 36 Preparing assignments 1 30 30 Preparing presentations 1 20 20 Final 1 2 2 Midterm 1 2 2 TOTAL WORKLOAD (hours) 300

Contribution of Learning Outcomes to Programme Outcomes

PO/LO PO.1 PO.2 PO.3 PO.4 PO.5 PO.6 PO.7 PO.8 PO.9 PO.10 PO.11 PO.12 PO.13 PO.14 PO.15 PO.16 PO.17 LO.1 5 5 5 5 LO.2 5 4 5 5 5 LO.3 5 5 LO.4 5 5 LO.5 5 5