COURSE UNIT TITLE

: DEMYELINATING DISEASES

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
SBI 6082 DEMYELINATING DISEASES ELECTIVE 4 0 0 12

Offered By

Basic Neuroscience

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

Offered to

Basic Neuroscience

Course Objective

To examine the classification, pathogenesis, clinical and laboratory features, differential diagnosis and treatment of demyelinating diseases from a multidisciplinary perspective.

Learning Outcomes of the Course Unit

1   To know the frequency, risk factors, and classification of demyelinating diseases
2   Understanding the multisciplinary approach to diagnosing demyelinating diseases
3   To know the diagnosis and treatment of multiple sclerosis
4   To know the frequency and measurement of cognitive involvement in multiple sclerosis

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Epidemiology of Demyelinating Diseases Multiple Sclerosis and Cognition
2 Classification of Demyelinating Diseases Multiple Sclerosis and Disability
3 Multiple Sclerosis Etiology, Types Multiple Sclerosis and Special Conditions (Childhood, Relationship with Gender)
4 Diagnosis, Diagnostic Criteria of Multiple Sclerosis Neuromyelitis Optica - Diagnosis
5 Diagnostic Methods in Multiple Sclerosis: Magnetic Resonance Imaging Neuromyelitis Optica - Treatment
6 Diagnostic Methods in Multiple Sclerosis: Cerebrospinal Fluid
7 Differential Diagnosis of Multiple Sclerosis
8 Multiple Sclerosis Treatment: Attack
9 Multiple Sclerosis Treatment: Disease-Modifying Treatments
10 Multiple Sclerosis Treatment: Symptomatic Treatment

Recomended or Required Reading

Multiple sclerosis a review. R Dobson, G Giovannoni - European journal of neurology, 2019 - Wiley Online Library
1. Depression in multiple sclerosis: a review. RJ Siegert, DA Abernethy - Journal of Neurology, Neurosurgery & , 2005 - jnnp.bmj.com
2. Cognitive dysfunction in multiple sclerosis: a review of recent developments. JA Bobholz, SM Rao - Current opinion in neurology, 2003 - journals.lww.com
3. The neuropsychiatry of multiple sclerosis: a review of recent developments. O Ghaffar, A Feinstein - Current opinion in psychiatry, 2007 - journals.lww.com
4. Disease modifying treatments for multiple sclerosis a review of approved medications. Ø Torkildsen, KM Myhr, L Bø - European journal of neurology, 2016
5. Mortality in multiple sclerosis: a review. P Ragonese, P Aridon, G Salemi - European Journal of , 2008 - Wiley Online Library
6. The geographic distribution of multiple sclerosis: a review. GC Ebers, AD Sadovnick - Neuroepidemiology, 1993 - karger.com
7. Benign course in multiple sclerosis: a review. GSM Ramsaransing, J De Keyser - Acta Neurologica , 2006 - Wiley Online Library
8. Treatment of multiple sclerosis: a review. SL Hauser, BAC Cree - The American Journal of Medicine, 2020 - Elsevier
9. Influence of temperature changes on multiple sclerosis: critical review of mechanisms and research potential. TC Guthrie, DA Nelson - Journal of the neurological sciences, 1995 - Elsevier
10. Evidenced-based cognitive rehabilitation for persons with multiple sclerosis: a review of the literature. AR O'Brien, N Chiaravalloti, Y Goverover - Archives of physical , 2008 - Elsevier
11. Environmental risk factors for multiple sclerosis: a review with a focus on molecular mechanisms. C O'Gorman, R Lucas, B Taylor - International journal of molecular , 2012 - mdpi.com
12. Epstein Barr virus infection and multiple sclerosis: a review. A Ascherio, KL Munger - Journal of Neuroimmune Pharmacology, 2010 - Springer
13. The psychology of fatigue in patients with multiple sclerosis: a review. Y Bol, AA Duits, RMM Hupperts, JWS Vlaeyen - Journal of , 2009 Elsevier.
14. MRI in multiple sclerosis: a review of the current literature. A Ceccarelli, R Bakshi, M Neema - Current opinion in neurology, 2012 - journals.lww.com

Planned Learning Activities and Teaching Methods

Presentation
Case presentations
Homework
Literature discussion

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 ASG ASSIGNMENT
2 PAR PARTICIPATION
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE ODV * 0.20 + DKL * 0.10 + FN* 0.70
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) ODV * 0.20 + DKL * 0.10 + FCGR* 0.70


*** Resit Exam is Not Administered in Institutions Where Resit is not Applicable.

Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

e-posta: serkan.ozakbas@deu.edu.tr
4124064

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 4 56
Preparations before/after weekly lectures 14 4 56
Final 1 2 2
TOTAL WORKLOAD (hours) 114

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12PO.13PO.14PO.15PO.16PO.17
LO.155
LO.2555
LO.34
LO.45555555555

CONTACT INFORMATION
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Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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