COURSE UNIT TITLE

: PRINCIPLES OF CLINICAL TOXICOLOGY

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
FAR 6061 PRINCIPLES OF CLINICAL TOXICOLOGY ELECTIVE 1 2 0 6

Offered By

Pharmacology

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR DOCTOR YEŞIM TUNÇOK

Offered to

Audiology
Laboratory Animal Science
Anatomy
Molecular Pathology
Exercise Physiology
Toxicology
Biochemistry
Biomechanics
Histology and Embryology
Medical Biology and Genetics
Biophysics
Physiology
Translational Oncology
Medical Parasitology
Microbiology
Pharmacology
Basic Neuroscience
Molecular Medicine
Translational Oncology
Molecular Medicine

Course Objective

To have knowledge about definition and history about toxicology, to learn basic concepts of toxicology, to know toxicity mechanism, to have knowledge abot toxicokinetic and toxicodynamic, to make risk assesment. To describe the laboratory methods in poisonings

Learning Outcomes of the Course Unit

1   To describe the Toxicokinetic, toxicodynamic and toxic syndromes
2   To learn the general approach of poisonings
3   To understand the description and treatment principles
4   To describe the antidotes and principles of use
5   To describe the laboratory methods in poisonings

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Description and general principles of Clinical Toxicology
2 Toxicokinetic and toxicodynamic
3 Poisons in workplace and risk evaluation
4 General principles approach to of acute poisonings (Gastrointestinal decontamination, laboratory, antidotes)
5 Heavy metal poisonings (Mercury, lead etc)
6 Toxic gases (carbonmonoxide, hydrogen sulphur)
7 Poisoning with caustics
8 Poisoning with cardiovascular toxins
9 Poisoning with antidepressants
10 Poisoning with analgesics (Paracetamol, salycylate)
11 Poisoning with sedative-hypnotics
12 Poisoning with antiepileptic drugs
13 Toxic plants
14 Poisoning with pesticides

Recomended or Required Reading

Textbook(s):
Goldfrank LR, Flomenbaum NE, Lewin NA, Howland MA, Hoffman RS, Nelson LS,eds. Goldfrank s Toxicology Emergencies. 7th ed. USA: McGraw-Hill Companies; 2006, pp 1469-1556.
Supplementary Book(s):
POISINDEX® System: Klasco RK (Ed): POSINDEX® System. Thomson Micromedex, Greenwood Village, Colorado
2.Poisoning & Drug Overdose. Fifth Ed. New York: McGraw-Hill Companies, 2006
References:
Materials:

Planned Learning Activities and Teaching Methods

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 PRF PERFORMANCE
2 FIN FINAL EXAM
3 FCG FINAL COURSE GRADE PRF * 0.40 + FIN*0.60
4 RST RESIT
5 FCGR FINAL COURSE GRADE (RESIT) PRF * 0.40 + FCGR*0.60


*** Resit Exam is Not Administered in Institutions Where Resit is not Applicable.

Further Notes About Assessment Methods

Working in Poison Information Center and present at least 10 cases that admitted to Poison Information center

Assessment Criteria

To be succesful in final exam and, to present a topic in course outline as a report

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

yesim.tuncok@deu.edu.tr, Tel: 4123903

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 2 28
Practice (Care Plan) 14 1 14
Preparations before/after weekly lectures 14 5 70
Preparation for final exam 1 20 20
Preparing presentations 1 20 20
Final 1 2 2
TOTAL WORKLOAD (hours) 154

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10
LO.1
LO.2
LO.3
LO.4
LO.52