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Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS FAR 6068 MECHANISMS OF DUGS ELECTIVE 1 0 0 3

Offered By

Pharmacology

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR DOCTOR AYŞE GELAL

Offered to

Pharmacology

Course Objective

To learn basic mechanism of interaction between drugs and living systems.

Learning Outcomes of the Course Unit

1   Receptor mediated actions of drugs 2   Ion channel mediated actions of drugs 3   Enzyme mediated actions of drugs 4   Mechanism of action contractig and relaxing drugs 5   Mechanisms of drug-drug interactions (drug-drug interactions, drug-food interactions) 6   Pharmacological methods

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description 1 How drugs act: general principles I (kinetics of receptor-drug interaction) 2 How drugs act: general principles II (agonism, antagonism, synergism, desensitisation and tachyphylaxis) 3 Receptor mediated actions of drugsI (ionotropic receptors) 4 Receptor mediated actions of drugs II (metabotropic receptors) 5 Receptor mediated actions of drugs III ( kinase-linked and related receptors) 6 Receptor mediated actions of drugs IV (nuclear receptors) 7 Ion channel mediated actions of drugs I (calcium channels) 8 Ion channel mediated actions of drugs II (sodium and potassium channels) 9 Enzyme mediated actions of drugs 10 Transport protein mediated actions of drugs 11 Other mechanisms of actions of drugs 12 How drugs act: cellular aspects-excitation, contraction. Contractig and relaxing drugs 13 Mechanism of drug interactions 14 Method and measurement in pharmacology 15 Method and measurement in pharmacology-2 16 Final

Recomended or Required Reading

1. Kayaalp O. Rasyonel tedavi yönünden Tıbbi Farmakoloji. 12. baskı, Ankara: Feryal matbaacılık; 2009. 2. B. Katzung. Basic and Clinical Pharmacology. McGraw-Hill. 12th ed. 2011. 3. Brunton L, Chabner B, Knollman B. Goodman & Gilman's The Pharmacological Basis of Therapeutics. McGraw-Hill. 12th ed. 2011. 4. Rang HP, Dale MM, Ritter JM, Flower RJ, Henderson G. Rang and Dale s Pharmacology. 7th ed. 2012

Planned Learning Activities and Teaching Methods

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA 1 PRF PERFORMANCE 2 FIN FINAL EXAM 3 FCG FINAL COURSE GRADE PRF * 0.40 + FIN*0.60 4 RST RESIT 5 FCGR FINAL COURSE GRADE (RESIT) PRF * 0.40 + FCGR*0.60 *** Resit Exam is Not Administered in Institutions Where Resit is not Applicable.

Further Notes About Assessment Methods

To be succesful in final exam and, to present a topic in course outline as a lecture

Assessment Criteria

To be succesful in final exam and, to present a topic in course outline as a lecture

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

ayse.gelal@deu.edu.tr, Tel: 4123904

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours) Lectures 15 2 30 Preparations before/after weekly lectures 15 2 30 Preparation for final exam 1 10 10 Preparing presentations 1 10 10 Final 1 1 1 TOTAL WORKLOAD (hours) 81

Contribution of Learning Outcomes to Programme Outcomes

PO/LO PO.1 PO.2 PO.3 PO.4 PO.5 PO.6 PO.7 PO.8 PO.9 PO.10 LO.1 5 5 1 5 5 1 3 1 2 1 LO.2 5 5 5 5 5 1 3 1 2 1 LO.3 5 5 5 5 5 1 3 1 2 1 LO.4 5 5 5 5 5 1 3 1 2 1 LO.5 5 5 5 5 5 1 3 1 2 1 LO.6 5 5 5 5 1 1 3 1 2 1