Dokuz Eylül University Information Package / Courses Catalog

Description of Individual Course Units

Course Unit Code	Course Unit Title	Type Of Course	D	U	L	ECTS
KIM 6103	BIOCHEMICAL VIEW ON TOXICOLOGY	ELECTIVE	3	0	0	7

Offered By

Graduate School of Natural and Applied Sciences

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR DOCTOR MÜNIRE NALAN DEMIR

Offered to

M.Sc.Biochemistry
Chemistry
Chemistry
Ph.D in Biochemistry

Course Objective

This course aims to inform exposure to the toxic agents (poisons), mechanisms of toxicity, organ toxicity and toxicity test, and factors effecting toxicity.

Learning Outcomes of the Course Unit

1	classify toxic agents and to compare exposure via inhalation, skin and gastrointestinal ways,
2	explain accumulations of xenobiotics on organs such as liver, kidney and bone and excretions of xenobiotics via renal, hepatic and exhalation,
3	learn toxicokinetic models, kinetics related to doses and kinetics in the repetition of exposure,
4	discuss mechanisms of toxicity (binding to receptors, binding to enzymes, binding other molecules, binding small molecules or ions, inhibition of energy production on a cell),
5	learn toxicity tests and discuss factors effecting toxicity from the view of chemical substances, exposure ways, type of organism and environmental factors.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week	Subject	Description
1	General information about toxicology and toxic agents,
2	Classification of toxic agents
3	Exposure ways to toxic agents
4	Accumulation on organs
5	Barrier systems
6	Excretion ways of toxic agents
7	Toxicokinetic models
8	Mechanisms of toxicity
9	Mechanisms of toxicity
10	Organ toxicity
11	Organ toxicity
12	Toxicity tests
13	Factors affecting toxicity
14	General evaluation and presentation

Recomended or Required Reading

1. Toxicology. Edited By: Hans Marquardt, Siegfried G. Schäfer, Roger Mcclellan And Frank Welsch, Academıc Press 1999 [ISBN: 978-0-12-473270-4].
2. Toksikoloji, Nevin Vural, Ankara Üniversitesi Basımevi 2005, [I S B N : 975 - 4 8 2- 2 8 9 1].

Planned Learning Activities and Teaching Methods

The course is taught in a lecture, class presentation and discussion format. All class members are expected to attend and both the lecture and seminar hours and take part in the discussion sessions. Besides the taught lecture, group presentations are to be prepared by the groups assigned for that week and presented to open a discussion session.

Assessment Methods

SORTING NUMBER	SHORT CODE	LONG CODE	FORMULA
1	PRS	PRESENTATION
2	ASG	ASSIGNMENT
3	FCG	FINAL COURSE GRADE	PRS * 0.50 + ASG * 0.50

*** Resit Exam is Not Administered in Institutions Where Resit is not Applicable.

Further Notes About Assessment Methods

None

Assessment Criteria

The students performance will be evaluated by the questions that will be asked in midterm (20%) and final exams (40%) and homework (40%).

Language of Instruction

English

Course Policies and Rules

Attendance to at least 70% for the lectures is an essential requirement of this course and is the responsibility of the student. It is necessary that attendance to the lecture on time. Any unethical behaviour that occurs either in presentations or in exams will be dealt with as outlined in school policy. You can find the undergraduate policy at http://web.deu.edu.tr/fen

Contact Details for the Lecturer(s)

Dokuz Eylul University, Faculty of Science, Department of Chemistry
e-mail: nalan.tuzmen@deu.edu.tr

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities	Number	Time (hours)	Total Work Load (hours)
Lectures	13	3	39
Preparations before/after weekly lectures	13	6	78
Preparing assignments	1	25	25
Preparing presentations	1	25	25
Preparing assignments	0	0	0
Final Assignment	1	2	2
Project Final Presentation	1	2	2
TOTAL WORKLOAD (hours)			171

Contribution of Learning Outcomes to Programme Outcomes

PO/LO	PO.1	PO.2	PO.3	PO.4	PO.5	PO.6	PO.7	PO.8	PO.9	PO.10	PO.11
LO.1	4	5	5	1	1	3	3	3	4	5	4
LO.2	4	5	5	1	1	3	3	3	4	5	4
LO.3	5	5	5	4	3	4	3	3	4	5	4
LO.4	4	5	5	1	1	3	3	3	4	5	4
LO.5	4	5	5	4	4	4	3	3	4	5	4

COURSE UNIT TITLE

DEGREE PROGRAMMES

Description of Individual Course Units

Offered By

Level of Course Unit

Course Coordinator

Offered to

Course Objective

Learning Outcomes of the Course Unit

Mode of Delivery

Prerequisites and Co-requisites

Recomended Optional Programme Components

Course Contents

Recomended or Required Reading

Planned Learning Activities and Teaching Methods

Assessment Methods

Further Notes About Assessment Methods

Assessment Criteria

Language of Instruction

Course Policies and Rules

Contact Details for the Lecturer(s)

Office Hours

Work Placement(s)

Workload Calculation

Contribution of Learning Outcomes to Programme Outcomes

CONTACT INFORMATION