COURSE UNIT TITLE

: METABOLIC REGULATION

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
KIM 5109 METABOLIC REGULATION ELECTIVE 3 0 0 8

Offered By

Graduate School of Natural and Applied Sciences

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR DOCTOR MÜNIRE NALAN DEMIR

Offered to

M.Sc.Biochemistry
Chemistry
Chemistry
Ph.D in Biochemistry

Course Objective

This course aims to investigate enzymatic, genetic and hormonal regulation mechanisms of metabolic pathways, metabolic behaviour in starvation and exercise and metabolic disorders.

Learning Outcomes of the Course Unit

1   Learn metabolic regulation with enzyme activity, control and regulation of enzyme reactions,
2   Discuss and compare controls of carbohydrate, lipids and nitrogen metabolisms with enzyme activities, explain genetic regulation of metabolism with gen expression,
3   Explain hormonal regulation with receptors,
4   Discuss answers and adaptations strategy of metabolism to the extraordinary conditions such as starvation, thickness and exercise,
5   Classify disorders and metabolic diseases such as disorders of carbohydrate and amino acids metabolism, diseases of glycogen and lipid metabolism.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 General view of metabolism and regulation, mechanisms of regulation and control
2 Metabolic regulation with enzymes, control and regulation of enzyme reactions
3 Control of carbohydrate metabolism with enzyme activity
4 Control of fatty acid metabolism with enzyme activity
5 Control of nitrogen metabolism with enzyme activity
6 Genetic regulation of metabolism: regulation and control of gen expression
7 Hormonal regulation of metabolism: receptors, types of receptor, hormones and metabolism
8 Midterm exam
9 Hormones affecting the regulation of metabolism
10 Digestion and absorption: organs in digestion, digestion and absorption of carbohydrates, digestion and absorption of lipids, digestion and absorption of proteins, absorption of water and electrolyte
11 Adaptations of metabolism to extraordinary conditions: Starvation and metabolic answer, thickness and metabolic answer, exercise and metabolic answer
12 Metabolic disorders: disorders of carbohydrate metabolism, disorders of glycogen metabolism
13 Metabolic disorders: disorders of lipid metabolism, diseases of amino acid metabolism
14 General evaluation and presentation of homework

Recomended or Required Reading

1. Telefoncu, A., Değer, O., Kılınç, A., Çolak, A., 2008, Metabolizmanın regülasyonu ve Metabolik Bozukluklar, Ege Üniversitesi Basımevi,Izmir.
2. Voet D., Voet J., 1995, Biochemistry, John Wiley & Sons, Inc.
3. Nelson, D.L., Cox, M.M., 2003, Principles of Biochemistry, Third Edition, Worth Publisher.
4. Murray, R.K, Mayes, P.A., Granner, D. K, Rodwell, V.W., 2003, Harper s Illustrated Biochemistry, McGraw-Hill Publishing

Planned Learning Activities and Teaching Methods

The course is taught in a lecture, class presentation and discussion format. All class members are expected to attend and both the lecture and seminar hours and take part in the discussion sessions. Besides the taught lecture, group presentations are to be prepared by the groups assigned for that week and presented to open a discussion session.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 ASG ASSIGNMENT
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE MTE * 0.20 + ASG * 0.40 + FIN * 0.40
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.20 + ASG * 0.40 + RST * 0.40


*** Resit Exam is Not Administered in Institutions Where Resit is not Applicable.

Further Notes About Assessment Methods

None

Assessment Criteria

The students performance will be evaluated by the questions that will be asked in midterm (20%) and final exams (40%) and homework (40%).

Language of Instruction

English

Course Policies and Rules

Attendance to at least 70% for the lectures is an essential requirement of this course and is the responsibility of the student. It is necessary that attendance to the lecture on time. Any unethical behaviour that occurs either in presentations or in exams will be dealt with as outlined in school policy. You can find the undergraduate policy at http://web.deu.edu.tr/fen

Contact Details for the Lecturer(s)

Dokuz Eylul University, Faculty of Science, Department of Chemistry
e-mail: nalan.tuzmen@deu.edu.tr

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 13 3 39
Preparations before/after weekly lectures 13 3 39
Preparation for midterm exam 1 20 20
Preparation for final exam 1 30 30
Preparing assignments 2 35 70
Final 1 2 2
Midterm 1 2 2
TOTAL WORKLOAD (hours) 202

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11
LO.145333334455
LO.225333334455
LO.325333334455
LO.425333334455
LO.525343444455

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

Copyright 2015 DEÜ. BİD

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