COURSE UNIT TITLE

: BIODEGRADATION AND BIOTRANSFORMATION OF ORGANIC SUBSTANCES

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
BYT 5007 BIODEGRADATION AND BIOTRANSFORMATION OF ORGANIC SUBSTANCES ELECTIVE 2 0 0 7

Offered By

Graduate School of Natural and Applied Sciences

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR DOCTOR ILGI KARAPINAR

Offered to

Ph.D. in Biotechnology
Ph.D. in Biotechnology
M.Sc. Metallurgical and Material Engineering
Metallurgical and Material Engineering
Metallurgical and Material Engineering
BIOTECHNOLOGY

Course Objective

The main objectives of the course are to describe the microbial degradation and conversion pathways of some environmentally important organic compounds such as polycyclic aromatic hydrocarbons, halogenated organic substances, xenobiotics etc., to discuss the microbial cultures and enzymes involved in biodegradation and bioconversion of these organic substances and to define the end products or by products generated at the end of the biotransformation.

Learning Outcomes of the Course Unit

1   List the recalsitrant toxic organic pollutant and their negative effects on the environment
2   Describe the factors effecting biodegradation of toxic organic compounds
3   State the function and properties of enzymes taks place in biodegradation of recalcitrant substances
4   Differentiate the specific microbial metbolic pathways for biodegradation
5   Identify the intermediate and end products of biodegradation pathways

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Microbial Perspective
2 Chemical structure of some environmental organic pollutants
3 Anaerobic Biodegradation of Hydrocarbons
4 Anaerobic Biodegradation of Hydrocarbons
5 Anaerobic Biodegradation and Biotransformation of Polycyclic Aromatic Hydrocarbons
6 Anaerobic Biodegradation and Biotransformation of Polycyclic Aromatic Hydrocarbons 6.1.1. Growth on PAHs 6.1.2. PAH Mineralization in the Absence of Growth 6.1.3. Incomplete Metabolism 6.1.4. Substrate Interactions in Pure Cultures 6.1.5. Diversity of PAH Metabolism
7 MIDTERM EXAM
8 Biodegradation of Halogenated Organic Compounds
9 Biodegradation of N-Containing Xenobiotics
10 Specific Enzymes in Biodegradation
11 Specific Enzymes in Biodegradation
12 Metabolic Logic and Pathways Maps
13 Metabolic Logic and Pathways Maps
14 Presentations

Recomended or Required Reading

Biocatalysis and biodegradation: Microbial transformation of organic compounds. Lawrence P. Wacett, C. Dougles Hershberger ASM Press Washington DC. USA 2000.
Biodegradation and Bioremediation. A Singh, O.P. Wards. Springer, Germany, 2004
Biotransformations: Microbial Degradation of Health Risk Compounds
Biotransformations: Bioremediation Technology for Health and Environmental Protection
Scientific literature

Planned Learning Activities and Teaching Methods

The course is taught in a lecture, class presentation and discussion format. The students are expected to prepare and present a term paper to open discussion session

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 ASG ASSIGNMENT
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE MTE * 0.25 + ASG *0.25 +FIN *0.50
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.25 + ASG *0.25 +RST *0.50


*** Resit Exam is Not Administered in Institutions Where Resit is not Applicable.

Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

English

Course Policies and Rules

The students have to attand the courses and they have to prepare a presentation

Contact Details for the Lecturer(s)

Prof.Dr.Ilgi KAPDAN
Room Number: Department of Environemnatl Engineering Room Number A 219
e-mail: ilgi.karapinar@deu.edu.tr

Office Hours

Will be announced

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 13 2 26
Preparations before/after weekly lectures 13 4 52
Preparation for midterm exam 1 25 25
Preparing assignments 1 30 30
Preparation for final exam 1 30 30
Midterm 1 2 2
Final 1 2 2
TOTAL WORKLOAD (hours) 167

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12
LO.123
LO.223
LO.323
LO.423
LO.523

CONTACT INFORMATION
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Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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