COURSE UNIT TITLE

Offered By

Translational Oncology

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR DOCTOR YASEMIN BAŞBINAR

Offered to

Translational Oncology

Course Objective

In vitro cancer models stand out as important tools for cancer research, and serve as low-cost screening platforms, especially for the acquisition of knowledge about new treatments. A key component of in vitro cancer models is a source of cancer cells. Cancer cell lines are easy to grow, allow direct comparison of experimental results, and are widely used to study the molecular mechanisms of tumor cell biology. In vitro models of solid tumors vary in complexity and range from tumor-derived cell lines to 3-dimensional models. Models are created to provide mechanistic insight into tumor growth/proliferation, migration, invasion, matrix remodeling, somnolence, intravascular, extravascular, angiogenesis, and drug delivery. Advances in tumor cell biology, 3D cell culture, tissue engineering, biomaterials, microfabrication, and microfluidics have led to the rapid development of in vitro tumor models. The new models are characterized by increased heterogeneity through the inclusion of multiple cell types (co-culture), ECM materials and soluble factors, facilitating the modeling of cancer. (References: Front Bioeng Biotechnol. 2016;4:12. Pharmaceutics. 2011;3(1):107-24. Cancer Res. 2007;67(8):3594-600. Cancer Res. 2011;13(4): 215.)

Learning Outcomes of the Course Unit

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Recomended or Required Reading

To be announced.

Planned Learning Activities and Teaching Methods

Assessment Methods

Further Notes About Assessment Methods

None

Assessment Criteria

With homework and presentation (LO 3,4, 5,and 6)
With Laboratory practice (LO 1,2, and 3)
With exam (LO 1,2,3,4,5, and 6)

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

e-mail: yasemin.baskin@deu.edu.tr : 0 232 412 8231

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Contribution of Learning Outcomes to Programme Outcomes