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Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS ELECTIVE

Offered By

Translational Oncology

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

ASSOCIATE PROFESSOR MELTEM ALPER

Offered to

Translational Oncology

Course Objective

The aim of the course to teach the mechanisms that play critical role in the regulation of the transcription, translation and post translationonal levels .

Learning Outcomes of the Course Unit

1   Be able to learn transcriptional and post-transcriptional mechanisms 2   Be able to learn prokaryotic transcription mechanism 3   Be able to learn eukaryotic transcription mechanism 4   Be able to learn the mechanism of the translation. 5   Be able to learn the regulation of the gene expression in prokaryotic and eukaryotic organisms 6   Be able to learn the epigenetic mechanisms and the regulatory RNAs

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description 1 Transkripsiyonel ve Post Transkripsiyonel Mekanizmalara Giriş Ökaryotlarda Gen Ekspresyonunun Regülasyonu-2 2 Prokaryotik Transkripsiyon Mekanizması-1 Ökaryotlarda Gen Ekspresyonunun Regülasyonu-3 3 Prokaryotik Transkripsiyon Mekanizması-1 Epigenetik 4 Ökaryotik Transkripsiyon Mekanizması-2 Regülatör RNA 5 RNA Splays ve Işleme Mekanizmaları 6 mRNA Stabilitesi ve Lokalizasyonu, Katalitik RNA 7 Translasyonun Mekanizması-1 8 Translasyonun Mekanizması-2 9 Prokaryotlarda Gen Ekspresyonunun Regülasyonu-Operonlar 10 Ökaryotlarda Gen Ekspresyonunun Regülasyonu-1

Recomended or Required Reading

To be announced.

Planned Learning Activities and Teaching Methods

Theoretical lectures, reinforcement and discussion of the subjects with in-class activities (presentations and assignments)

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA 1 PRF PERFORMANCE 2 FIN FINAL EXAM 3 FCG FINAL COURSE GRADE PRF * 0.40 + FIN*0.60 4 RST RESIT 5 FCGR FINAL COURSE GRADE (RESIT) PRF * 0.40 + FCGR*0.60

Further Notes About Assessment Methods

None

Assessment Criteria

Assessment with homework and PRESENTATION (Learning outcome 1,2 and 3) Assessment with the exam (Learning outcome1,2,3 4,5 and 6)

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

To be announced.

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours) Lectures 15 3 45 Preparations before/after weekly lectures 15 2 30 Preparation for final exam 5 5 25 Preparing assignments 4 2 8 Preparing presentations 5 8 40 Final 1 2 2 TOTAL WORKLOAD (hours) 150

Contribution of Learning Outcomes to Programme Outcomes

PO/LO PO.1 PO.2 PO.3 PO.4 PO.5 PO.6 PO.7 PO.8 PO.9 PO.10 PO.11 PO.12 LO.1 5 5 5 5 5 5 LO.2 5 5 5 5 5 LO.3 5 5 5 5 5 LO.4 5 5 5 5 5 LO.5 5 5 5 5 5 LO.6 5 5 5 5 5