COURSE UNIT TITLE

: THE BASIC OF TRANSLATIONAL ONCOLOGY

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
TRO 5011 THE BASIC OF TRANSLATIONAL ONCOLOGY ELECTIVE 4 2 0 12

Offered By

Translational Oncology

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR DOCTOR YASEMIN BAŞBINAR

Offered to

Translational Oncology
Translational Oncology

Course Objective

"from the lab to the bedside of cancer" overview, molecular approaches in risk assessment and individual risk assessment, Organospecific biomarker concept, identification of therapeutic targets in cancer, from cancer biology to cancer clinic research models will be discussed

Learning Outcomes of the Course Unit

1   Recognize and understand the general outline of cancer
2   Carcinogenesis can be expressed in general terms
3   Recognize and understand the detection of cancer
4   Recognize and understand the general outline of cancer treatment
5   Recognize and understand the general approach of translational oncology
6   Be able to know the molecular approach in risk assessment and individual risk assessment.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Presentation of course and Concepts
2 "From the laboratory to the bedside of cancer" overview
3 Molecular approaches in risk assessment 1
4 Molecular approaches in risk assessment 2
5 Individual risk assessment 1
6 Individual risk assessment 2
7 The concept of Organospecific biomarker 1
8 The concept of Organospecific biomarker 2
9 The concept of Organospecific biomarker 3
10 Identification of therapeutic targets in cancer 1
11 Identification of therapeutic targets in cancer 2
12 Identification of therapeutic targets in cancer 3
13 From cancer biology to clinical cancer research models 1
14 From cancer biology to clinical cancer research models 2
15 Debates

Recomended or Required Reading

Molecular Biology of the Cell, 6th Edition. Ed. Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter. Garland Publishers
Essential Cell Biology - 4th Edition Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander D Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter Garland Publishers
The Biology of Cancer, 2nd Edition, Robert A. Weinberg, Garland Publishers
Molecular Biology of the Gene, 7th edition, James Watson, Alexander Gann, Tania Baker, Michael Levine, Stephan Bell, Richard Losick, Stephan Harrison Pearson Cold Spring harbor Laboratory Press.
Principles of Molecular Diagnostics and Personalized Cancer Medicine, Dongfeng Tan, henry Lynch, Wolters Kluwer, Lippincott Williams&Wilkins.
The Handbook of Biomarkers, Kewal Jain, Humana Press
Translational and Experimental Clinical Research, Daniel Schuster, William Powers, Lippincott Williams&Wilkins.
Klinik Araştırmalar Kitabı 2014, Hamdi Akan, Hilal Ilbars, Nurşah Çetinkaya, Bilimsel Tıp Yayınevi
Designing Clinical Research 4th Edition, Steven R Cummings , Warren S Browner , Deborah G Grady , Thomas B Newman , Dr Stephen B Hulley, Lippincott Williams&Wilkins.
Journals
Clinical & translational oncology (1699-048X) in Springer
Translational oncology (1944-7124) in PubMed

Planned Learning Activities and Teaching Methods

Lectures, the topics with classroom activities (presentations and homework assignments) to consolidate and discussion

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 PRF PERFORMANCE
2 FIN FINAL EXAM
3 FCG FINAL COURSE GRADE PRF * 0.40 + FIN*0.60
4 RST RESIT
5 FCGR FINAL COURSE GRADE (RESIT) PRF * 0.40 + FCGR*0.60


Further Notes About Assessment Methods

None

Assessment Criteria

1. The learner will clearly define outlined LO1,LO2, LO3, LO4 which will evaluate with exam.
2. The learner will recognize, LO5, LO6 will evaluate with homework, prepared presentations by themselves and exam.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Prof Dr Yasemin Başbınar
yasemin.baskin@deu.edu.tr ; 0 232 412 58 01

Office Hours

Monday 11:00-12:00

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 15 6 90
Preparations before/after weekly lectures 15 14 210
Final 1 1 1
TOTAL WORKLOAD (hours) 301

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12
LO.1555
LO.2555
LO.3555
LO.4555
LO.5555
LO.6555