COURSE UNIT TITLE

: TRANSLATIONAL MOLECULER EPIDEMIOLOGY OF CANCERS

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
TRO 5012 TRANSLATIONAL MOLECULER EPIDEMIOLOGY OF CANCERS ELECTIVE 3 0 0 6

Offered By

Translational Oncology

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR DOCTOR YASEMIN BAŞBINAR

Offered to

Translational Oncology
Translational Oncology

Course Objective

Definition of cancer, cancer development, genetic predisposition, environmental influences, microbiology and cancer, history of cancer epidemiology, cancer epidemiology in world , cancer epidemiology in Türkiye, fundamental cancer epidemiology epidemiological outcomes of cancer and clinical cancer relations whole genome analysis and the translation to systems biology will be discussed.

Learning Outcomes of the Course Unit

1   Recognize and understand the general outline of carcinogenesis.
2   Be able to know the cancer epidemiology.
3   Be able to critically evaluate the published literature in the field of the epidemiology
4   Interprets the research results in cancer epidemiology
5   Be able to know of the general outline of molecular epidemiology
6   Recognize and understand the translation from the whole genome analysis and systems biology to clinical outcomes.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 The definition of cancer
2 Cancer development process
3 Genetic predisposition
4 Environmental effects
5 Microbiology and cancer
6 History of cancer epidemiology
7 Epidemiology of cancer in the World
8 Epidemiology of cancer in Türkiye
9 Basic concepts in cancer epidemiology studies
10 Molecular cancer epidemiology 1
11 Molecular cancer epidemiology 2
12 Interpretation of the results in epidemiological cancer1
13 Interpretation of the results in epidemiological cancer2
14 Relationships of whole genome analysis and clinical cancer 1
15 Relationships of whole genome analysis and clinical cancer 2

Recomended or Required Reading

Molecular Biology of the Cell, 6th Edition. Ed. Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter. Garland Publishers
Essential Cell Biology - 4th Edition Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander D Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter Garland Publishers
The Biology of Cancer, 2nd Edition, Robert A. Weinberg, Garland Publishers
Molecular Biology of the Gene, 7th edition, James Watson, Alexander Gann, Tania Baker, Michael Levine, Stephan Bell, Richard Losick, Stephan Harrison Pearson Cold Spring harbor Laboratory Press.
Principles of Molecular Diagnostics and Personalized Cancer Medicine, Dongfeng Tan, henry Lynch, Wolters Kluwer, Lippincott Williams&Wilkins.
The Handbook of Biomarkers, Kewal Jain, Humana Press
Translational and Experimental Clinical Research, Daniel Schuster, William Powers, Lippincott Williams&Wilkins.

Planned Learning Activities and Teaching Methods

Lectures, the topics with classroom activities (presentations and homework assignments) to consolidate and discussion

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 PRF PERFORMANCE
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE MTE * 0.20 +PRF * 0.20 + FIN* 0.60
5 RST RESIT
6 FCGR FINAL COURSE GRADE MTE * 0.20 +PRF * 0.20 +RST* 0.60


Further Notes About Assessment Methods

None

Assessment Criteria

1. The learner will clearly define outlined LO1, LO2, LO5, which will evaluate with exam.
2. The learner will recognize, LO3, LO4, LO6 will evaluate with homework, prepared presentations by themselves and exam.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

ender ellidokuz@deu.edu.tr ; 0 232 412 37 99

Office Hours

Monday 13:00-14:00

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 15 3 45
Preparations before/after weekly lectures 15 3 45
Preparation for midterm exam 1 8 8
Preparation for final exam 1 10 10
Preparing assignments 4 5 20
Preparing presentations 2 10 20
Final 1 1 1
Midterm 1 1 1
TOTAL WORKLOAD (hours) 150

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12
LO.15555
LO.25555
LO.35555
LO.45555
LO.55555
LO.6555