COURSE UNIT TITLE

: BIOCHEMICAL DIAGNOSIS OF THE ROLE AND IMPORTANCE AT THE TRANSLATIONAL MEDICINE

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
TRT 5018 BIOCHEMICAL DIAGNOSIS OF THE ROLE AND IMPORTANCE AT THE TRANSLATIONAL MEDICINE COMPULSORY 2 2 0 3

Offered By

TRANSLATIONAL MEDICINE

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR DOCTOR MUALLA AYLIN ARICI

Offered to

TRANSLATIONAL MEDICINE

Course Objective

To learn the concept of biomarker and personalized medicine, to understand the procedure of translating the omics data obtained by modern technologies into clinical applications.

Learning Outcomes of the Course Unit

1   Biochemical diagnosis , understanding of the place of diagnosis and treatment of diseases
2   Understanding the importance of biochemical mekanizmalr Translayonel medicine for the research stage
3   Understanding the biochemical changes in the course of the disease
4   Learning the basic information about the biochemical methods and techniques
5   Recognition of the methods used for statistical analysis of biochemical data

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Biochemistry ve Clinical Medicine
2 Cell
3 Water and Electrolyte Homeostasis
4 Acid-Base Balance
5 Amino Acids and Proteins
6 Enzymes
7 Mid-exam
8 Carbohydrates and Lipids
9 Bioenergetics and Oxidative Metabolism
10 Nutrition, Vitamins and Minerals
11 Lipoprotein Metabolism and Atherogenesis
12 Nucleic Acids
13 Biochemical Endocrinology, and Neurochemistry
14 Cell Growth and Cancer
15 Final exam

Recomended or Required Reading

1. Becker RC, Smyth S. Biomarker science: on a theme of personalized medicine. J Thromb Thrombolysis. 2012 Jul;34(1):141-2. doi: 10.1007/s11239-012-0726-6.
2. Sathyanath Rajasekharan, Amit Bar-Or. From bench to MS bedside: Challenges translating biomarker discovery to clinical practice. Journal of Neuroimmunology 248 (2012) 66 72.
3. Zineh I, Huang SM. Biomarkers in drug development and regulation: a paradigm for clinical implementation of personalized medicine. Biomark Med. 2011 Dec;5(6):705-13. doi: 10.2217/bmm.11.90.
4. Zhang A, Sun H, Wang P, Han Y, Wang X. Modern analytical techniques in metabolomics analysis. Analyst. 2012 Jan 21;137(2):293-300. doi: 10.1039/c1an15605e. Epub 2011 Nov 21.
5. La Thangue NB, Kerr DJ. Predictive biomarkers: a paradigm shift towards personalized cancer medicine. Nat Rev Clin Oncol. 2011 Aug 23;8(10):587-96. doi: 10.1038/nrclinonc.2011.121.

Planned Learning Activities and Teaching Methods

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 PRF PERFORMANCE
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE MTE * 0.20 +PRF * 0.30 + FIN* 0.50
5 RST RESIT
6 FCGR FINAL COURSE GRADE MTE * 0.20 +PRF * 0.30 +RST* 0.50


Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Doç.Dr Zübeyde ERBAYRAKTAR
zubeyde.erbayrakatar@gmail.com

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 2 28
Preparations before/after weekly lectures 14 1 14
Preparation for midterm exam 1 10 10
Preparation for final exam 1 10 10
Preparation for quiz etc. 1 4 4
Preparing assignments 5 1 5
Final 1 2 2
Midterm 1 2 2
TOTAL WORKLOAD (hours) 75

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9
LO.1544344554
LO.2544344554
LO.3544345545
LO.4544345445
LO.5544345445

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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