COURSE UNIT TITLE

: LABORATORY ROTATION IN MOLECULAR MEDICINE

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
MOT 6050 LABORATORY ROTATION IN MOLECULAR MEDICINE ELECTIVE 1 4 0 8

Offered By

Molecular Medicine

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

ASSOCIATE PROFESSOR GAMZE TUNA

Offered to

Molecular Medicine
Molecular Medicine

Course Objective

The aim of this course is to allow the students to rotate in different laboratories
related with the MSc programme in molecular medicine in a multidisciplinary
perpective, to learn about the different research methods and techniques used in
clinical laboratory and to acquire practical knowledge in this area.

Learning Outcomes of the Course Unit

1   To know about the different laboratories which may be involved in molecular medicine
2   To learn about the different subjects and areas of application in these laboratiores
3   To understand the basic principles of techniques used in these laboratories
4   To compare different methods in terms of principles and applications
5   To be able to apply these methods in ones own research field
6   To integrate the information acquired and prepare an oral presentation

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Course Introduction Basic Principles, Types and Applications of Chromatography (T) MDA measurement by HPLC method (P)
2 Analytical method validity
3 Clinical Laboratories 1: Central Laboratory Adjustment, Urine, Gaita Investigations, autoanalysis
4 Clinical Laboratories 2: Hormone Analyzes
5 New Methods in Molecular Medicine 1
6 New Methods in Molecular Medicine 2
7 Mid term exam
8 Molecular Biological Techniques
9 Molecular Cytogenetic Methods
10 Molecular Cytogenetic Methods
11 Laboratory for Pathology
12 Histological research methods (T) TEM Enhancements and Basic Principles, fixes and fixatives in TEM TEMPERS used in TEM and preparation, Embedding Materials, Transition from Light Microscope to TEM, Blade preparation, Thick sectioning, Dyeing and evaluation in fine microscope, Trim or mesa, Thin sectioning, TEM dyes and dyeing methods, TEM imaging and Image processing (P)
13 Basic Oncology Laboratory
14 LC-MS / MS Applications (T) Extraction of damaged DNA nucleosides, measurement and quantitation of DNA nucleosides(P)
15 GC / MS and GC-MS / MS (T) EDTA leukocyte isolation, Leukocyte DNA isolation, Measurement and quantification of damaged DNA bases in DNA samples by GC-MS (P).
16 FINAL

Recomended or Required Reading

. Biomedical Science Practice-Experimentla and Professional skills (Edited by Hedley
Glencross, Nessar Ahmed and Qiuyu Wang). Oxford University press. 2011
2. Tietz Klinik Kimyada Teme Ilkeler (Beşinci Baskıdan Çeviri) Editörler: Catl A.
Burtis- Edward R. Ashwood Çeviri Editörü: Diler Aslan. Palme Yayıncılık. 2005
3. Articles on laboratory methods published in SCI or expanded SCI journals.

Planned Learning Activities and Teaching Methods

Face -to- Face

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 PRF PERFORMANCE
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE MTE * 0.20 +PRF * 0.30 + FIN* 0.50
5 RST RESIT
6 FCGR FINAL COURSE GRADE MTE * 0.20 +PRF * 0.30 +RST* 0.50


Further Notes About Assessment Methods

If needed, other assessment methods can be added to the table given below.

Assessment Criteria

Understanding, learning, analyse, compare, actively contribution

Language of Instruction

Turkish

Course Policies and Rules

Actively contribution in class

Contact Details for the Lecturer(s)

e-mail: gamze.tuna@deu.edu.tr
Phone: 412 2605

Office Hours

Tuesday 12.30-13:30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 1 14
Tutorials 14 4 56
Preparations before/after weekly lectures 2 5 10
Preparation for midterm exam 14 2 28
Preparation for final exam 20 2 40
Preparing presentations 10 4 40
Preparing the laboratory notebook 4 3 12
TOTAL WORKLOAD (hours) 200

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12PO.13PO.14
LO.144553343343335
LO.244555555554555
LO.344554444444555
LO.455555554544555
LO.555555555544555
LO.655555555555445

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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