COURSE UNIT TITLE

: MOLECULAR METABOLISM

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
MOT 6040 MOLECULAR METABOLISM ELECTIVE 3 0 0 9

Offered By

Molecular Medicine

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR DOCTOR ZAHIDE ÇAVDAR

Offered to

Molecular Medicine
Molecular Medicine

Course Objective

In the aims of the course to learn the carbohydrate, lipid and protein metabolisms; to realize the metabolic pathways with the clinical cases with metabolic disease.

Learning Outcomes of the Course Unit

1   Understand the carbohydrate metabolism
2   Understand the lipid metabolism
3   Understand the protein metabolism
4   Be able to integrate the metabolic pathways
5   Analyze critically metabolic disease pathogenesis (with the samples of the patients with common metabolic disorders) and discuss the pathogenesis of these disorders with the laboratory findings.
6   Understand the regulation of the energy metabolism
7   Understand and discuss energy production in the mitochondria.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Principles of bioenergetics, Oxidative phosphorylation, Carbohydrate metabolism-1, Carbohydrate metabolism -2
2 Lipid Metabolism, Bacterial metabolism, Aminoacid Metabolism,
3 Nücleotide Metabolism, Protein Metabolism, Diabetes (Metabolism during fasting and well-fed state)

Recomended or Required Reading

1. Lehninger Biyokimyanın Ilkeleri. Michael M. Cox, David L. Nelson. Palme Yayıncılık. 2005
2. Textbook of Biochemistry with Clinical Correlations. Thomas M. Devlin. Sixth Edition. 2006
3. Inborn Metabolic Diseases (4th edition). Fernandes J, Saudubray JM, Berghe G, Walter JH, Springer Medizin Verlag, Heidelberg, 2006.
4. Hoffmann GF, Nyhan WL, Zschocke J, Kahler SG, Mayatepek E. Inherited metabolic disease. Philadelphia: Lippincott Williams and Wilkins; 2002.
5. Harper s Illustrated Biochemistry 28th Edition, 2009 , Murray, Bender, Rotham, Kennelly Rodwell and Weil.McGraw Hill International Edition.pp51-83.

Planned Learning Activities and Teaching Methods

The course will be run in an integrated way-winding theory with case discussion and laboratory practicals. The methods of learning will be interactive.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 ASG ASSIGNMENT
3 PAR PARTICIPATION
4 FIN FINAL EXAM
5 FCGR FINAL COURSE GRADE MTE * 0.30 + ASG * 0.20 +PAR* 0.10 + FIN*0.40
6 RST RESIT
7 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.30 + ASG * 0.20 +PAR* 0.10 + RST*0.40


Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

Turkish

Course Policies and Rules

The student is expected to read the resources before coming to class. In addition, he/she is expected to contribute actively to discussion, group-work and practicals. Plagiarism of any type will result in disciplinary action.

Contact Details for the Lecturer(s)

Nur Arslan:
Phone: 0090 232 412 61 07

Office Hours

Mondays 12.30-13.30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 45 1 45
Preparations before/after weekly lectures 45 3 135
Preparation for final exam 1 14 14
Preparation for quiz etc. 1 10 10
Preparing presentations 1 8 8
Preparing assignments 1 10 10
Final 1 2 2
Quiz etc. 1 1 1
TOTAL WORKLOAD (hours) 225

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12PO.13PO.14
LO.1555
LO.2555
LO.3555
LO.45555
LO.55555
LO.655
LO.755