COURSE UNIT TITLE

: METABOLISM I

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
BIO 6070 METABOLISM I ELECTIVE 2 0 0 6

Offered By

Biochemistry

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR DOCTOR AYŞE SEMRA KOÇTÜRK

Offered to

Biochemistry

Course Objective

The aim of this course is the acquisition of basic knowledge about metabolism. Trainers will get knowledge about on energy resources of the cell, catabolic reactions, oxidative phosphorylation and metabolism of some building blocks (purine, pyrimidine) and some proteins derived from amino acids, coagulation mechanism and coagulation proteins. All learning outlines will be supported by problem based learning techniques.

Learning Outcomes of the Course Unit

1   Be able to comprehend and understand of the principles of metabolism of a cell. (Knowledge).
2   Be able to have a basic theoretical knowledge on cellular metabolism (Knowledge) .
3   Be able to analyses information related with cellular metabolism (Analysis)
4   Be able to interpret metabolism related problems on various models (Synthesis)
5   Be able to present the research findings and academic topics related to metabolism to academic and non-academic community. (Communication)

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Principles of Bioenergetics
2 Glycolysis and the catabolism of Hexose I
3 Glycolysis and the catabolism of Hexose II
4 The citric acid and Glyoxylate cycles
5 Shuttle system and oxidative phosphorylation
6 Case- study with Group Pyruvate Dehydrogenase Deficiency Fumarase Deficiency Mitochondrial Myopathy Leber Hereditary Optic Neuropathy Electron Transport Chain
7 Case- study with Group Diabetes mellitus Important of 2,3-bisphosphoglycerate Lactic acidosis Arsenic Poisoning
8 Case- study with Group Fructose intolerance Galactosemia Wernicke-Korsakoff syndrome Glycogen Storage Diseases
9 Nucleic acids, synthesis and catabolism
10 Case- study with Group Nucleic acids metabolism
11 Amino Acids Structure and Classification, protein absorption and digestion, synthesis
12 Synthesis of amino acids
13 Catabolism of amino acids
14 Amino Acid-Related Compounds
15 Case- study with Group Cystinuria, Cystinosis Homocystinuria Phenylketonuria

Recomended or Required Reading

1.Nelson DL, Cox MM. Lehninger Principles of Biochemistry.Third editon Worth Publishers, New York, 2000.
2. Devlin TM. Texbook of Biochemistry with Clinical Correlations.Fifth edition. Wiley-Liss, New York,2002.
3. Meisenberg G, Simmons WH.Principles of Medical Biochemistry.Mosby Inc., St.Louis, Missouri, 1998.
4. Baynes J, Dominiczak MH. Medical Biochemistry.Mosby Inc., London 1999.
5. Marks DB, Marks AD, Simth CM. Basic Medical Biochemistry.A. Clinical Approach. Williams &Wilkins, Baltimore, Maryland, 1996
6. Onat, Emerk K,Sözmen E.Insan Biyokimyası, Palme Yayıncılık, Ankara, 2002
7. Gürdöl F, Ademoğlu E. Biyokimya, Nobel Tıp Kitapevleri, Istanbul 2006.

Planned Learning Activities and Teaching Methods

Theoretical lectures and problem based learning sessions with a scenario for the comprehension of metabolism.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 PRF PERFORMANCE
2 FIN FINAL EXAM
3 FCG FINAL COURSE GRADE PRF * 0.40 + FIN*0.60
4 RST RESIT
5 FCGR FINAL COURSE GRADE (RESIT) PRF * 0.40 + FCGR*0.60


Further Notes About Assessment Methods

None

Assessment Criteria

1. Basic information on the cellular metabolism of learner will be evaluated with final exam and their performance in PBL session.
2. The ability of learner to merge and to interpret the metabolism-related theoretical information in scenarios will be evaluated in group works.
3. The competence of learner on communication and information transfer will be evaluated by PBL sessions.

Language of Instruction

Turkish

Course Policies and Rules

Optional, if the instructor needs to add some explanation or further note, this column can be selected from the DEBIS menu.

Contact Details for the Lecturer(s)

semra.kocturk@deu.edu.tr, 4124407

Office Hours

on Tuesday at: 13.30-16.30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 10 2 20
Tutorials 10 2 20
Preparations before/after weekly lectures 2 10 20
Preparation for final exam 1 20 20
Preparation to PBL Session 7 10 70
Final 1 3 3
TOTAL WORKLOAD (hours) 153

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12PO.13
LO.155
LO.255
LO.34
LO.44
LO.55

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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