COURSE UNIT TITLE

: METABOLISM II

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
BIO 6066 METABOLISM II ELECTIVE 3 0 0 9

Offered By

Biochemistry

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

Offered to

Biochemistry

Course Objective

The aim of this course is the acquisition of general properties of lipids, metabolism of lipids and carbohydrates; biochemistry of nutrition and the metabolic disorders

Learning Outcomes of the Course Unit

1   Be able to classify lipids and define their general properties, structure, nomenclature and function.
2   Be able to explain the metabolism of lipids and lipoproteins and their regulation.
3   Be able to explain glycolysis, gluconeogenesis, glycogenesis, glycogenolysis and pentose phosphate pathway and their regulation.
4   Be able to comprehend the regulation of blood glucose level.
5   Be able to classify vitamins and their functions.
6   Be able to explain the basic principles and biochemical markers of nutrition.
7   Be able to associate metabolism in fed and fasting state.
8   Be able to explain the disorders of oxidation.
9   Be able to explain the metabolic syndrome

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 General properties of lipids Fatty acids Fatty acid synthesis Phosphoglycerides and sphingolipids Intracellular degradation of lipids Role of lipids in signal transduction Eicosanoids Cholesterol metabolism Tryglycerides Lipoproteins and their metabolism
2 Case 1 Glycolysis Gluconeogenesis and regulation of blood glucose level Case2 Glycogenesis Glycogenolysis Pentose phosphate pathway
3 Case/Article Lipid soluble vitamins Water soluble vitamins Basic principles of nutrition Biochemical markers of nutrition Trace elements Metabolism in fed and fasting state Oxidation disorders Metabolic syndrome Case

Recomended or Required Reading

1. Smith C, Marks AD and Lieberman. Basic Medical Biochemistry. A Clinical Approach. Williams &Wilkins, Baltimore, Maryland, 2005
2. Nelson DL, Cox MM. Lehninger Principles of Biochemistry.Third editon Worth Publishers, New York, 2000.
3. Devlin TM. Texbook of Biochemistry with Clinical Correlations.Fifth edition. Wiley-Liss, New York, 2002.
4. Murray RK, Granner DK, Mayes PA and Rodwell VW. Harper s Illustrated Biochemistry. Mc Graw Hill, New York, 2003.

Planned Learning Activities and Teaching Methods

Theoretical lectures, case and article based learning sessions.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 FIN FINAL EXAM
2 FCG FINAL COURSE GRADE FIN*1
3 RST RESIT
4 FCGR FINAL COURSE GRADE (RESIT) RST*1


Further Notes About Assessment Methods

If the instructor needs to add some explanation or further note, this column can be selected from the DEBIS menu.

Assessment Criteria

Optional, if the instructor needs to add some explanation or further note, this column can be selected from the DEBIS menu.

Basic knowledge on the lipid, carbohydrate metabolism and nutrition and related disorders of learner will be evaluate with mid-term and final exams.

Language of Instruction

Turkish

Course Policies and Rules

Optional, if the instructor needs to add some explanation or further note, this column can be selected from the DEBIS menu.

Contact Details for the Lecturer(s)

banu.onvural@deu.edu.tr 0 232 4124420

Office Hours

on Tuesday at: 14.00-15.00

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 45 2 90
Preparations before/after weekly lectures 15 4 60
Preparing assignments 3 11 33
Reading 3 10 30
Final 3 4 12
TOTAL WORKLOAD (hours) 225

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12PO.13
LO.154
LO.254
LO.354
LO.4544
LO.554
LO.654
LO.7544
LO.854
LO.9444