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Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS TBG 6104 LIFE CYCLES AND DEATH OF CELLS ELECTIVE 2 0 0 6

Offered By

Medical Biology and Genetics

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR DOCTOR SEFA KIZILDAĞ

Offered to

Medical Biology and Genetics

Course Objective

The purpose of this course, students to train Mammalian cell cycle phases, the molecular mechanisms and their control checkpoints and theoretical knowledge about the mechanisms of apoptosis.

Learning Outcomes of the Course Unit

1   To discuss and compare, various types of tissue cells differences between the characteristics the division and similarities. 2   To explain the processes phases of the cell cycle and cell death in the natural and unnatural way 3   To describe and compare stages of the cell cycle and apoptosis, and autophagic cell death and Necroptosis types. 4   Explains the processes and mechanisms of cell cycle checkpoints. 5   To classifies types Apoptosis and autophagic cell death and Necroptosis. Students capable of describe this types of death changes in cell morphology. 6   To describe and comparing Apoptosis, autophagic cell death and Necroptosis techniques 7   To describe and compare the cell cycle checkpoints and techniques used in determining the mechanisms.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description 1 Introduction *Cell and viability *Biological properties of different cell types 2 Cell characteristics and life cycle 3 *Cell cycle phases *Cell cycle check points 4 *Cyclin and cyclin dependent kinases * Cancer and cell cycle 5 *Factors that affect the cell cycle 6 *Classification of types of cell death 7 *necroptosis *apoptosis *autophagy 8 student literature review presentation

Recomended or Required Reading

Textbook(s): Molecular Biology of THE CELL, B. Alberts, 2007 Supplementary Book(s): G.M.Cooper, The Cell A Molecular Approach, Second ed.,ASM Press, Sinauer Associates Inc., 2000 References: Materials:

Planned Learning Activities and Teaching Methods

Theoretical presentations will be given. Students are four times, will do a literature review.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA 1 PRF PERFORMANCE 2 FIN FINAL EXAM 3 FCG FINAL COURSE GRADE PRF * 0.40 + FIN*0.60 4 RST RESIT 5 FCGR FINAL COURSE GRADE (RESIT) PRF * 0.40 + FCGR*0.60

Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Tel: 412 4613 E-posta: sefa.kizildag@deu.edu.tr

Office Hours

Tuesday 15:30-17:00

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours) Lectures 15 1 15 Preparations before/after weekly lectures 15 3 45 Preparation for final exam 1 10 10 Preparing Individual Assignments 4 10 40 Preparing Presentations 6 6 36 Final 1 3 3 TOTAL WORKLOAD (hours) 149

Contribution of Learning Outcomes to Programme Outcomes

PO/LO PO.1 PO.2 PO.3 PO.4 PO.5 PO.6 PO.7 PO.8 PO.9 LO.1 1 3 LO.2 1 2 LO.3 1 LO.4 1 LO.5 1 3 5 LO.6 3 5 LO.7 3 5