COURSE UNIT TITLE

: STEM CELL HYPOTESIS AND CANCER

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
ONK 5035 STEM CELL HYPOTESIS AND CANCER ELECTIVE 1 0 0 3

Offered By

Basic Oncology

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR DOCTOR SAFIYE AKTAŞ

Offered to

Basic Oncology
Basic Oncology

Course Objective

The aim of this course is to understand the biology, molecular properties and genetics of cancer stem cell in a translational overview.

Learning Outcomes of the Course Unit

1   Capable of understanding stem cell.
2   Be able to explain sharing and different properties of cancer stem cell and normal stem cell.
3   Be able to learn role of cancer stem cell in cancer development.
4   Be able to know cancer stem cell related signalling pathways
5   Be able to explain role of stem cell in hematologic and solid cancers.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Defination of stem cell
2 Areas of stem cell usage
3 Properties of cancer stem cell
4 Cancer stem cell role in cancer development
5 Relationship of stem cell with metastasis
6 Microenviroment and cancer
7 Stem cell biomarkers
8 Stem cell identification technics
9 Stem cell isolation technics
10 Signalling pathways in cancer stem cell
11 Role of cancer stem cell in hematopoetic cancers
12 Role of cancer stem cell in adult solid cancers 13. Role of cancer stem cell in pediatric cancers 14. Role of cancer stem cell in therapy resistance 15. Therapoetic strategies against cancer stem cell 15. 14.

Recomended or Required Reading

1. Diagnostic Approach to Clinical Oncology Mario W. Fiorentino PICCIN 1999
2. Molecular Biology in Cancer Medicine. Razelle Kurzrock, Moshe Talpaz, Martin Dunitz 1995.
3. AJCC Cancer Staging Handbook.Irvin D. Fleming. Lippincott Willams & Wilkins 1998
4. Manual of Clinical Oncology. D.K. Hossfeld, C.D. Sherman, R.R. Love, F.X. Bosch Springer- Verlag, 1990 Fith Edition.
5. Pathologic Basis of Disease. Vinay Kumar, Abul K. Abbas, Nelson Fausto, Elsevier Saunderss, 2005 Seventh Edition
6. Molecular Mechanism of Cancer. Georg F. Weber, Springer 2007
7. The Biology of Cancer Robert A. Weinberg, Gariand Science 2007

Planned Learning Activities and Teaching Methods

Theoretical Lectures, Working for exams, Reading practices

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 PRF PERFORMANCE
2 FIN FINAL EXAM
3 FCG FINAL COURSE GRADE PRF * 0.40 + FIN*0.60
4 RST RESIT
5 FCGR FINAL COURSE GRADE (RESIT) PRF * 0.40 + FCGR*0.60


Further Notes About Assessment Methods

Learning outcomes will be assessed with classical questions of mid-term and final exams. The homework on the topic of reading and evaluating 5 different types of papers will help in evaluating the learner understood the topics or not.

Assessment Criteria

Learning outcomes will be assessed with classical questions of mid-term and final exams. The homework on the topic of reading and evaluating 5 different types of papers will help in evaluating the learner understood the topics or not.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

safiye.aktas@deu.edu.tr 28202

Office Hours

Tuesday at: 13.30-16.30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 15 1 15
Preparations before/after weekly lectures 15 2 30
Preparation for midterm exam 1 10 10
Preparation for final exam 1 16 16
Midterm 1 2 2
Final 1 2 2
TOTAL WORKLOAD (hours) 75

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10
LO.15
LO.25
LO.35
LO.45
LO.55

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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