COURSE UNIT TITLE

: BASIC ONCOLOGY

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
ONK 5021 BASIC ONCOLOGY COMPULSORY 2 2 0 7

Offered By

Basic Oncology

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR DOCTOR SAFIYE AKTAŞ

Offered to

Basic Oncology
Basic Oncology

Course Objective

The aim of this course is to define basic oncology and understand basic oncology knowledge. The adaptation to basic oncology laboratory and basic principles and rules of laboratory work is planned to be tought.

Learning Outcomes of the Course Unit

1   Capable of understanding relationship of cell cycle and cancer.
2   Be able to recognize basic knowledge of cell death mechanisms, invasion and metastasis in cancer.
3   Be able to understand the importance of signalling pathways in cancer.
4   Be able to understand gene-cancer relationship and importance of genes in cancer diagnosis, therapy and follow-up.
5   . Be able to apply basic laboratory work; cancer cell culture, Nucleic acid isolation, PCR and mutation analysis.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Defination of Basic Oncology and its role in Oncology Practice. Laboratory: Rules and Principles of Basic Oncology Laboratory
2 Cell death and control in cancer Laboratory: Learning how to use laboratory equipments
3 Cell Cycle and Cancer Laboratory: Learning how to use laboratory materials
4 Multistep Carcinogenesis Laboratory: Working Safety in lab
5 Biology of invasion and metastasis Laboratory: Storage in lab, using refrigirators
6 Cancer related signalling pathway changes Laboratory: Working Clean in lab
7 Basic Knowledge of DNA damage and repair Laboratory: Using Spectrophotometer
8 Tumor immunologic methods Laboratory: TIL isolation
9 Personalizied medicine in cancer Laboratory: DNA extraction
10 (Molecular methods in cancer treatment Laboratory. DNA quality assesment
11 (Regulation of cancer related genes Laboratory: PCR
12 Molecular biology of epithelial tumor Laboratory: Mutation analysis
13 Molecular biology of mesenchimal tumors Laboratory: Cancer cell culture
14 Molecular biology of neuroendocrine tumors Laboratory: Apoptosis Assesment

Recomended or Required Reading

1. Use and Interpretation of Laboratory Tests in Oncology. Douglas C. Aziz, Specialty Laboratories. Third edition 1998
2. Tumor Models in Cancer Research Beverly A. Teicher Humana Pres 2002
3. Pathologic Basis of Disease. Vinay Kumar, Abul K. Abbas, Nelson Fausto, Elsevier Saunderss, 2005 Seventh Edition
4. Molecular Mechanism of Cancer. Georg F. Weber, Springer 2007
5. The Biology of Cancer Robert A. Weinberg, Gariand Science 2007

Planned Learning Activities and Teaching Methods

Theoretical Lectures, Giving a homework, Working for exams, Reading practices , laboratory applications

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 PRF PERFORMANCE
3 FIN FINAL EXAM
4 FCGR FINAL COURSE GRADE MTE * 0.30 + PRF* 0.30 + FIN* 0.40
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.30 + PRF* 0.30 + RST* 0.40


Further Notes About Assessment Methods

None

Assessment Criteria

Evaluation will be made with questions in the midterm and final exams related to theoretical courses and laboratory applications. In a certain type of cancer (for example: breast cancer, lung cancer, colon cancer), the study of a diagnostic or prognostic or research parameter by PCR will be prepared in a scientific format, and the comprehension of theoretical and laboratory knowledge will be measured.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

090-2324125891

Office Hours

Monday 12.30-13.30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 2 28
Tutorials 14 2 28
Preparations before/after weekly lectures 12 2 24
Preparation for midterm exam 1 15 15
Preparation for final exam 1 25 25
Preparing assignments 1 47 47
Midterm 1 4 4
Final 1 4 4
TOTAL WORKLOAD (hours) 175

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10
LO.155
LO.255
LO.355
LO.455
LO.55

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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