COURSE UNIT TITLE

: CELL SIGNAL TRANSDUCTION MECHANISMS

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
ELECTIVE

Offered By

Graduate School of Natural and Applied Sciences

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

ASSOCIATE PROFESSOR PELIN BALÇIK ERÇIN

Offered to

Ph.D. in Biology
Biology

Course Objective

This course aims to teach the signal transduction properties and functions

Learning Outcomes of the Course Unit

1   1. The graduate is able to define the basics of signal transduction biology
2   2. The graduate is able to define the signal types, and recognize the different characteristics of the signaling molecules.
3   3. The graduate will learn the details of the different signaling pathways and related diseases.
4   4. The graduate is able to define apoptosis signal pathways and markers

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Introduction to signal transduction
2 Cellular signaling molecules
3 Cell surface molecules
4 Receptor tyrosine kinases
5 Literature presentation and discussion
6 Intracellular signal transduction
7 MAPK pathway
8 Literature presentation and discussion
9 Review
10 Signaling mechanisms controlling cell proliferation and differentiation-I
11 Signaling mechanisms controlling cell proliferation and differentiation-II
12 Pathways of apoptosis
13 Signal transduction and cancer
14 Literature presentation and discussion
15 Final exam

Recomended or Required Reading

1-D.L. Nelson, M.M.Cox, Lehninger Principles of Biochemistry, Worth Publisher, 6th Edition, 2013.
2-D. Batien et al. Signal Transduction, Elsevier Academic Press, 2005.
3-J.W. Wang and R. Casero, Cell Signalling. Physiology, Pharmacology and CancerResearch.
Humana Press, 2006.

Planned Learning Activities and Teaching Methods

The course is taught in a lecture, class presentation and discussion format. All class members are expected to attend and both the lecture and take part in the discussion sessions. Besides the taught lecture, group presentations are to be prepared by the groups assigned for that week and presented to open a discussion session.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 FIN FINAL EXAM
3 FCG FINAL COURSE GRADE MTE * 0.40 + FIN * 0.60
4 RST RESIT
5 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.40 + RST * 0.60


Further Notes About Assessment Methods

None

Assessment Criteria

Student will be evaluated with midterm and final exam.

Language of Instruction

Turkish

Course Policies and Rules

Attendance to at least 70% for the lectures is an essential requirement of this course and is the responsibility of the student. It is necessary that attendance to the lecture and homework delivery must be on time. Any unethical behavior that occurs either in presentations or in exams will be dealt with as outlined in school policy

Contact Details for the Lecturer(s)

pelin.balcikercin@deu.edu.tr

Office Hours

will be announced

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 3 42
Preparations before/after weekly lectures 14 3 42
Preparation for midterm exam 1 14 14
Preparation for final exam 1 14 14
Preparing assignments 14 3 42
Preparing presentations 6 3 18
Final 1 3 3
Midterm 1 3 3
TOTAL WORKLOAD (hours) 178

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12
LO.14
LO.24
LO.3434
LO.44

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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