COURSE UNIT TITLE

: CELL AND TISSUE ENGINEERING

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
BYM 0546 CELL AND TISSUE ENGINEERING ELECTIVE 3 0 0 8

Offered By

Graduate School of Natural and Applied Sciences

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR DOCTOR MEHMET KUNTALP

Offered to

Ph.D. in Biotechnology
Industrial Ph.D. Program In Advanced Biomedical Technologies
Industrial Ph.D. Program In Advanced Biomedical Technologies
Biomedical Tehnologies (English)
Ph.D. in Biotechnology
BIOTECHNOLOGY

Course Objective

The course aims to teach the students the principles of cell and tissue engineering with a focus on understanding the fundamental interactions between cells and their environment

Learning Outcomes of the Course Unit

1   Learning the basic definitions of cell and tissue engineering, main concepts, stem cells, biodegradable scaffolds, cell and biomaterial interactions
2   Learning the main components of tissue engineering, basis of selection parameters for those components, production and evaluation methods and potential clinical applications
3   Review of biomaterials and evaluation of biocompatibility
4   Improving the research, analysis, comparison and criticizing capabilities of the students in current applications of tissue engineering, and enhancing their ability to propose alternative solutions
5   Improving the students ability to introduce their knowledge to others gained by their research for term projects by means of classroom presentations
6   Recognizing the interdisciplinary approach among the clinic and research activities in the area, and analyzing the sample solution producing approaches between medical doctors, life scientists and engineers
7   Discussion of ethical issues in tissue engineering

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Natural examples of Tissue Engineering, Embryogenesis, development
2 Stem Cells and their importance for tissue engineering; Adult stem cells, Embryonic stem cells
3 Remodeling and Wound Healing
4 Tissue Regeneration
5 Tissue engineering scaffolds; Selection, Production, Properties
6 Factors controlling cell and tissue growth and differentiation; Growth Factors, ECM
7 Cell-cell interactions Receptor/ligand interactions Cell-biomaterial interactions
8 MIDTERM EXAM
9 Cellular mechanics
10 Gene expression in cells
11 Bioreactor design and advanced instrumentation
12 -Bone, Cartilage, Vascular grafts -Heart, Liver, Nerve -Applications of Tissue Engineering:
13 Constraints of tissue engineered systems; Biological, Physical, Chemical
14 Homework and Presentations

Recomended or Required Reading

Current scientific and review papers
Robert Lanza, Robert Langer, Joseph P. Vacanti, Principles of Tissue Engineering,
Elsevier N. Ashammakhi, P. Ferretti, R. Reis, eds. Topics in Tissue Engineering, e-book

Planned Learning Activities and Teaching Methods

1. Presentation
2. Question-answer technique
3. Homework

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 ASG ASSIGNMENT
3 PRS PRESENTATION
4 FIN FINAL EXAM
5 FCG FINAL COURSE GRADE MTE* 0.30 + ASG * 0.20 + PRS * 0.10 + FIN * 0.40
6 RST RESIT
7 FCGR FINAL COURSE GRADE (RESIT) MTE* 0.30 + ASG * 0.20 + PRS * 0.10 + RST * 0.40


Further Notes About Assessment Methods

None

Assessment Criteria

Meaningful learning of the basic concepts given in presentations, association of concepts with each other, establishing the cause-result relationships and making comments by using the information available for problems and evaluating idea generation are carried out with mid-term and final exams, homework and presentations.

Language of Instruction

English

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Ege University, Bioengineering Dept.
Assist.Prof.Dr. Aylin Şendemir Ürkmez
aylin.sendemir@ege.edu.tr

Office Hours

To be announced

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 13 3 39
Preparations before/after weekly lectures 13 5 65
Preparation for final exam 1 30 30
Preparation for midterm exam 1 25 25
Preparing assignments 1 25 25
Midterm 1 2 2
Final 1 2 2
TOTAL WORKLOAD (hours) 188

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10
LO.15453442
LO.2554553554
LO.344545
LO.453555432
LO.525355253
LO.6345555453
LO.74545543