COURSE UNIT TITLE

: XENOBIOTICS AND THEIR METABOLIC EFFECTS

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
KIM 6104 XENOBIOTICS AND THEIR METABOLIC EFFECTS ELECTIVE 3 0 0 7

Offered By

Graduate School of Natural and Applied Sciences

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR DOCTOR MÜNIRE NALAN DEMIR

Offered to

M.Sc.Biochemistry
Chemistry
Chemistry
Ph.D in Biochemistry

Course Objective

The aim of this courses is to introduce xenobiotics which is not a natural component of the organism and to investigate its metabolism and biological effects.

Learning Outcomes of the Course Unit

1   To be able to learn transition of xenobiotics to ecosystem
2   To be able to explain dispersion rules and biotransformation of xenobiotics
3   To able to compare biological effects of aliphatic and aromatic hydrocarbons
4   To be able to clarify the metabolic effects of pesticides, metals, chemical and biological agents and natural compounds
5   To able to discuss the biological effects of active and passsive smoking

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Introduction to Xenobiotic
2 Transition of xenobiotics to ecosystem
3 Dispersion rules of xenobiotics
4 Biotransformation of xenobiotics
5 Biotransformation of xenobiotics
6 Toxic substances and their biological effects: Aliphatic hydrocarbons, aromatic hydrocarbons
7 Toxic substances and their biological effects: Pesticides and their metabolic effects
8 Assignment presentation
9 Toxic substances and their biological effects: Metals
10 Toxic substances and their biological effects: Chemical and biological agents
11 Toxic substances and their biological effects: Natural compounds
12 Toxic substances and their biological effects: Active and passive smoking
13 General evaluation
14 Assignment presentation

Recomended or Required Reading

1. Voet D., Voet J., Biochemistry, John Wiley & Sons, Inc, 1995
2. Environmental Toxicology: Impacts of Environmental Toxicants on Living Systems (Lewis Publishers) by Ming-Ho Yu. 2001. [ISBN: 1-56-670474-X]
3. Introduction to Environmental Toxicology: Impacts of Chemicals Upon Ecological Systems (Lewis Publishers) by Wayne G. Landis and Ming-Ho Yu. Third Edition. 2004. [ISBN: 1-56-670660-2]

Planned Learning Activities and Teaching Methods

The course is taught in a lecture, class presentation and discussion format. All class members are expected to attend and both the lecture and seminar hours and take part in the discussion sessions. Besides the taught lecture, group presentations are to be prepared by the groups assigned for that week and presented to open a discussion session.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 ASG ASSIGNMENT/PRESENTATION
2 FIN FINAL EXAM
3 FCG FINAL COURSE GRADE ASG * 0.40 +FIN * 0.60
4 RST RESIT
5 FCGR FINAL COURSE GRADE (RESIT) ASG * 0.40 +RST * 0.60


Further Notes About Assessment Methods

None

Assessment Criteria

The students performance will be evaluated by the questions that will be asked in midterm (20%) and final exams (40%) and homework (40%).

Language of Instruction

English

Course Policies and Rules

Attendance to at least 70% for the lectures is an essential requirement of this course and is the responsibility of the student. It is necessary that attendance to the lecture and homework delivery must be on time. Any unethical behavior that occurs either in presentations or in exams will be dealt with as outlined in school policy. You can find the undergraduate policy at http://web.deu.edu.tr/fen

Contact Details for the Lecturer(s)

Dokuz Eylul University, Faculty of Science, Department of Chemistry
e-mail: nalan.tuzmen@deu.edu.tr

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 13 3 39
Preparations before/after weekly lectures 13 3 39
Preparing assignments 1 30 30
Preparation for final exam 1 40 40
Preparing assignments 0 35 0
Final 1 2 2
Project Assignment 1 2 2
TOTAL WORKLOAD (hours) 152

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11
LO.145433343454
LO.245433343454
LO.345433343454
LO.445433343454
LO.545433343454