COURSE UNIT TITLE

: COURSE NAME: MOLECULAR GENETICS OF BACTERIA

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
ELECTIVE

Offered By

Graduate School of Natural and Applied Sciences

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR DOCTOR ARZU GÖRMEZ

Offered to

Ph.D. in Biology
Biology

Course Objective

This course aims to inform students about bacteria and bacterial genomes.

Learning Outcomes of the Course Unit

1   will be able to explain the cell structures of bacteria and their related molecular mechanisms.
2   will be able to explain gene transfers in bacteria.
3   will be able to give information about the bacterial genome.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 General Information of Bacteria I: Bacterial cell and cell wall, surface of bacterial cell, morphology and physiology of bacteria
2 General Information of Bacteria II: Cytoplasmic membrane and cytoplasm; Synthesis of peptidoglycan and Bacterial cell division
3 The bacterial chromosome; DNA Structure, Replication, and Segregation
4 Bacterial gene expression; Transcription, Translation, and Protein Folding
5 Bacterial genetic analysis; Fundamentals and current approaches
6 Bacterial genetic analysis; Mutations and mutants; Molecular principles of Mutations
7 Plasmids and Plasmid Replication: Characteristics of plasmids; plasmid characteristics and their application areas in gene cloning; Importance of plasmids for bacteria
8 Horizontal Gene Transfer Among Bacteria; Conjugation, Transformation, Transduction, Lytic & Lysogenic Conversion
9 Midterm exam
10 Transposons, Insertion Sequence, and Integrons
11 Molecular Mechanisms of Homologous Recombination
12 DNA Repair and Mutagenesis; Ames Test; Replica plate Test.
13 Regulation of Gene Expression: Genes and Operons, Global Regulation; Regulons and Stimulons
14 General Overview of Bacterial Genome; Scientific Research and Evaluation

Recomended or Required Reading

1. Snyder, L., Peters, J. E., Henkin, T.M., Champness, W., 2013. Molecular Genetics of Bacteria, 4th Edition.
2. Madigan, M.T., Martinko, J. M., Bender, K.S., Buckley, D.H., Stahl, D.A., 2015. Brock Biology of Microorganisms. 14th Edition.

Planned Learning Activities and Teaching Methods

The course is taught in a lecture, class presentation, and discussion format. All class members are expected to attend the lecture and participate in the discussion sessions. Besides the course, group presentations are to be prepared by the groups assigned for that week and presented to open a discussion session.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 ASG ASSIGNMENT
2 MTE MIDTERM EXAM
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE ASG * 0.30 + MTE * 0.30 + FIN * 0.40
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) ASG * 0.30 + MTE * 0.30 + RST * 0.40


Further Notes About Assessment Methods

None

Assessment Criteria

The student is evaluated with a midterm exam, research presentations, and a final assignment.

Language of Instruction

Turkish

Course Policies and Rules

It is the student's responsibility to attend 70% of the courses during the semester. Students are required to be present during the lesson and on the days when the presentation is required. Regarding unethical behaviors that may occur in classes and exams, action is taken within the framework of the relevant regulation. The regulation on the teaching and examination application principles of the DEU Institute of Science and Technology can be obtained from the address http://fbe.deu.edu.tr/.

Contact Details for the Lecturer(s)

arzu.gormez@deu.edu.tr

Office Hours

It will be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 13 3 39
Student Presentations 3 1 3
Preparations before/after weekly lectures 13 2 26
Preparation for midterm exam 1 15 15
Web Search and Library Research 3 8 24
Preparing presentations 3 4 12
Preparing assignments 1 20 20
Project Assignment 1 2 2
Midterm 1 1 1
Project Final Presentation 1 2 2
TOTAL WORKLOAD (hours) 144

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12
LO.154545445454
LO.244435455454
LO.3555435255445