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Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS BST 6020 BIOSENSORS FOR HEALTHCARE ELECTIVE 3 0 0 9

Offered By

Biomedicine and Health Technologies

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR DOCTOR SEDA NUR TOPKAYA ÇETIN

Offered to

Biomedicine and Health Technologies

Course Objective

Learning Outcomes of the Course Unit

1   1. Understand the fundamental principles underlying biosensor operation, including biochemical recognition, signal transduction, and system integration. 2   2. Analyze the components and architecture of biosensor systems, including bioreceptors, transducers, and signal processing units. 3   3. Quantitatively evaluate biosensor performance using key metrics such as sensitivity, specificity, limit of detection (LOD), linearity, and response time. 4   4. Compare and contrast different biosensing technologies, including electrochemical, optical, piezoelectric, and thermal approaches. 5   5. Design basic biosensor systems for specific applications by selecting appropriate materials, detection strategies, and transduction mechanisms. 6   6. Apply biosensor technologies to practical problems in biomedicine, environmental monitoring, bioprocess control, food safety, and biosecurity.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description 1 Introduction to Nanotechnology 2 Introduction to Biosensors 3 Biorecognition Elements 4 Transduction Mechanisms I: Electrochemical Biosensors 5 Transduction Mechanisms II: Optical Biosensors and Other Sensor Types 6 Biosensor Performance Metrics 7 Biomedical Applications of Biosensors 8 Midterm 9 Point of Care Tests 10 Applications of Point of Care Tests 11 Emerging Trends in Biosensor Technologies 12 Smartphone-Based, Flexible, And Paper-Based Biosensors 13 Hands-On Examples/Calculations & Open Discussion 14 Student Presentations- Design of a Point of Care Testing 15 Student Presentations- Design of a Point of Care Testing 16 Final Exam

Recomended or Required Reading

Point-of-care testing: Principles and Clinical Applications. Peter Luppa, Ralf Junker, Springer, 2018. Fundamentals of Biosensors in Healthcare, Md Saquib Hasnain, Amit Kumar Nayak and Tejraj M. Aminabhavi, 2024. Douglas A. Skoog, F. James Holler and Stanley R. Crouch Principles of Instrumental Analysis 7th Edition.

Planned Learning Activities and Teaching Methods

Face-to-face lectures, Interactive discussions and question-answer sessions, Group project Problem-solving and case analysis, Student presentations and mini projects, Homework assignments, Open discussions on emerging technologies.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA 1 ASG ASSIGNMENT 2 MTE MIDTERM EXAM 3 FIN FINAL EXAM 4 FCG FINAL COURSE GRADE ASG * 0.30 + MTE * 0.30 + FIN * 0.40 5 RST RESIT 6 FCGR FINAL COURSE GRADE (RESIT) ASG * 0.30 + MTE * 0.30 + RST * 0.40

Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

English

Course Policies and Rules

Attendance is mandatory.

Contact Details for the Lecturer(s)

sedanur.topkayacetin@deu.edu.tr

Office Hours

Tuesdays during 13.00-14.00

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours) Lectures 14 3 42 Group session 2 5 10 Preparation for midterm exam 14 3 42 Preparation for final exam 14 4 56 Preparing presentations 2 10 20 Preparing assignments 2 5 10 Midterm 1 5 5 Final Assignment 1 7 7 Quiz etc. 2 5 10 Project Final Presentation 2 10 20 TOTAL WORKLOAD (hours) 222

Contribution of Learning Outcomes to Programme Outcomes

PO/LO PO.1 PO.2 PO.3 PO.4 PO.5 PO.6 PO.7 PO.8 LO.1 5 4 5 4 3 3 3 2 LO.2 5 3 5 4 3 4 2 2 LO.3 4 4 5 4 3 5 2 2 LO.4 5 3 5 4 3 3 2 2 LO.5 5 3 5 5 4 4 3 3 LO.6 5 4 5 4 4 4 3 3