COURSE UNIT TITLE

: PRINCIPLES AND TECHNIQUES OF IMAGING

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
MBG 5034 PRINCIPLES AND TECHNIQUES OF IMAGING ELECTIVE 2 2 0 9

Offered By

Molecular Biology and Genetics

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

ASSOCIATE PROFESSOR SERHAT TOZBURUN

Offered to

Molecular Biology and Genetics
Biomedicine and Health Technologies
Molecular Biology and Genetics

Course Objective

Two-fold; (1) to develop a comprehensive understanding of imaging systems used today, and (2) to provide graduate students an introductory level review on the fundamental physics and engineering underlying each imaging modality and a broad overview on the current applications.

Learning Outcomes of the Course Unit

1   The students will understand the basics of imaging modalities covered in the course.
2   The students will appreciate novel technologies and applications in imaging practices.
3   The students will be able to describe the principles of physics behind imaging technology, radiation safety, and relevant applications.
4   The students will be able to discuss the strengths and weaknesses of the different imaging modalities.
5   The students will be able to list the major imaging technologies in clinical practices.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Introduction: History of imaging, and basic principles.
2 Principles of X-ray physics and X-ray and matter interactions
3 Computed tomography (CT) scans
4 Principle of magnetic resonance physics and Magnetic resonance imaging (MRI)
5 Electron microscopy (EM)
6 Principle of ultrasound physics and Ultrasound imaging
7 Introduction to light microscopy
8 Types of light microscopes
9 MIDTERM
10 Time-domain Optical Coherence Tomography
11 Fourier-domain Optical Coherence Tomography
12 Optical frequency domain imaging
13 Optical spectroscopy: Fluorescence spectroscopy and Infrared spectroscopy
14 Optical microscopy: Confocal and multi-photon microscopy
15 Comparing imaging methodologies and technologies, and current applications
16 Final exam

Recomended or Required Reading

Textbook(s): There is no single textbook available which specifically addressing the topics in the course. There are supplementary books, which include all material for this course comprehensively. Class notes will be available to students online by the links associated with each week.
Supplementary Book(s):
1) Biomedical Optics: Principles and Imaging by Lihong V. Wang and Hsin-i Wu; Wiley-Interscience, 1st edition, 2007. ISBN-13: 978-0471743040
2) Medical Imaging Physics by William R. Hendee and E. Russell Ritenour; Wiler-Liss, 4th edition, 2002. ISBN-13: 978-0471382263
3) Handbook of Biological Confocal Microscopy by James B. Pawley; Springer, 3rd edition, 2006. ISBN-13: 978-0387259215
4) Principles of Fluorescence Spectroscopy by Joseph R. Lakowicz; Springer, 3rd edition, 2011. ISBN-13: 978-0387259215
5) Molecular Imaging I by Wolfhard Semmler and Markus Schwaiger; Springer, Volume 185/I, 2008. Online ISBN: 978-3540727187

Planned Learning Activities and Teaching Methods

Discussion, active participation by students, individualization, theoretical studies, and literature review.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 FIN FINAL EXAM
3 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.50 + FIN *0.50
4 RST RESIT
5 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.50 + RST * 0.50


Further Notes About Assessment Methods

None

Assessment Criteria

Theoretical knowledge will be evaluated by exams and assignments.

Language of Instruction

English

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Email: serhat.tozburun@deu.edu.tr
Phone: 4126538

Office Hours

TBA

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 15 3 45
Tutorials 15 2 30
Preparations before/after weekly lectures 15 5 75
Preparation for midterm exam 1 25 25
Preparation for final exam 1 15 15
Preparing assignments 2 15 30
Final 1 2 2
Midterm 1 2 2
TOTAL WORKLOAD (hours) 224

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8
LO.1544
LO.2544
LO.3544
LO.4544
LO.5544

CONTACT INFORMATION
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Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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