COURSE UNIT TITLE

: BIOMATERIALS AND TISSUE ENGINEERING

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
MBG 5033 BIOMATERIALS AND TISSUE ENGINEERING ELECTIVE 3 0 0 9

Offered By

Molecular Biology and Genetics

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

ASSOCIATE PROFESSOR SINAN GÜVEN

Offered to

Molecular Biology and Genetics
Biomedicine and Health Technologies
Molecular Biology and Genetics

Course Objective

To learn the fundamental principles of biomaterials used in medicine
To learn the tissue engineering and regenerative medicine principles
To understand the novel therapeutic applications utilizing biomaterials and tissue engineering
To learn the potentials of stem cells in regenerative medicine

Learning Outcomes of the Course Unit

1   To understand the fundamental concepts and the properties of biomaterials in medicine
2   To distinguish the different biomaterials according target tissue
3   To understand host-material and cell-material interactions
4   To understand the how to implement novel biomaterials in clinics
5   To understand the tissue engineering approaches
6   To appreciate the potential of stem cells in regenerative medicine
7   To understand the clinical applications of tissue engineering
8   To acquire the ability to access, present and discuss the knowledge on tissue engineering

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Properties and classes of materials used in medicine-1
2 Properties and classes of materials used in medicine-2
3 Physicochemical modifications of materials
4 Host reaction to biomaterials
5 Biological testing of biomaterials
6 Degradation of materials in the biological environment
7 Applications of biomaterials
8 Mid-term exam
9 Introduction to tissue engineering
10 In vitro control of tissue development
11 Cell-material interaction and biomaterials in tissue engineering
12 Stem cells in tissue engineering
13 Top-down and bottom-up tissue engineering
14 Transplantation of engineered tissues
15 Clinical applications of tissue engineering
16 Final Exam

Recomended or Required Reading

Textbook(s):
Biomaterials Science, An Introduction to Materials in Medicine, 3rd edition B., Ratner, A.,Hoffman, F., Schoen, J., Lemons, Academic Press 2013.
Principles of Tissue Engineering, 4th edition, R., Lanza, R. Langer, J., Vacanti, Academic Press 2014.
Additional book information will be announced later.
References: Helpful reviews on the topics will be shared with students.

Planned Learning Activities and Teaching Methods

1. PowerPoint lecture presentations: Lecture subjects will be covered as PowerPoint presentations schematized and simplified for easy visual comprehension.
2. Research article presentation assignment: Students will choose recent research articles about essential or current repair and regeneration related topics, present the key points of the article as a short presentation and discuss those with the audience. All presentations will be held together on a predetermined date outside of lecture hours.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 ASG ASSIGNMENT
2 MTE MIDTERM EXAM
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE ASG * 0.30 + MTE * 0.30 + FIN * 0.40
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) ASG * 0.30 + MTE * 0.30 + RST * 0.40


Further Notes About Assessment Methods

An interactive participation of students is expected during the lectures.

Assessment Criteria

Mid-term and final exams: A high percentage (70%) of correct answers, showing that the lecture topics are well digested, is expected.
Oral presentation: The student is expected to understand and present a selected paper, state how well the paper sets forth the scientific question and put forward an idea on future perspectives.

Language of Instruction

English

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Tel: 0232 412 6561 Mobile: 0545 584 3337
E-mail: singuven@gmail.com

Office Hours

To be announced later

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 3 42
Preparations before/after weekly lectures 15 8 120
Preparation for midterm exam 1 10 10
Preparation for final exam 1 20 20
Preparing presentations 1 20 20
Final 1 3 3
Midterm 1 2 2
TOTAL WORKLOAD (hours) 217

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8
LO.15
LO.25
LO.355
LO.4
LO.55
LO.65
LO.75
LO.85