COURSE UNIT TITLE

: DOWNSTREAM PROCESSING

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
MBG 5039 DOWNSTREAM PROCESSING ELECTIVE 3 0 0 9

Offered By

Molecular Biology and Genetics

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

ASSOCIATE PROFESSOR HASAN BUĞRA ÇOBAN

Offered to

Molecular Biology and Genetics
Molecular Biology and Genetics

Course Objective

To provide an overview of the fundamentals of downstream processing in industrial productions.

Learning Outcomes of the Course Unit

1   To learn effective strategies of downstream processing based on characteristics of biomolecules
2   To understand general principles of down streaming methods
3   To gain knowledge of different methods and equipments used in the laboratory and industry
4   To be able to choose and apply appropriate down streaming methods on the basis of target product
5   To be able to make mathematical calculations about down streaming methods

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Introduction to bioproducts
2 Overview to down stream processing
3 Evaporation
4 Filtration
5 Centrifugation
6 Membrane separation
7 Extraction
8 Case studies
9 Midterm
10 Adsorption
11 Precipitation
12 Chromatography
13 Crystallization
14 Drying
15 Case studies
16 Final Exam

Recomended or Required Reading

Bioprocess Engineering Basic Concepts, Shuler and Kargi, Second Edition 2002, Prentice Hall.
Biochemical Engineering and Biotechnology, Ghasem Najafpour, First Edition, 2006, Elsevier Science.
Fermentation and Biochemical Engineering Handbook, Henry C. Vogel Celeste M. Todaro, Second Edition, 1996, William Andrew.

Planned Learning Activities and Teaching Methods

Theoretical lecture with PowerPoint, problem solving related to industrial level phenomenon, and hands-on experiences in the laboratory.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 ASG ASSIGNMENT
2 MTE MIDTERM EXAM
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE ASG * 0.20 + MTE * 0.30 + FIN * 0.50
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) ASG * 0.20 + MTE * 0.30 + RST * 0.50


Further Notes About Assessment Methods

None

Assessment Criteria

Theoretical and practical knowledge will be evaluated via written exams and laboratory work skills plus laboratory reports, respectively.

Language of Instruction

English

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

bugra.coban@deu.edu.tr

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 3 42
Preparations before/after weekly lectures 14 5 70
Preparation for midterm exam 1 15 15
Preparation for final exam 1 20 20
Preparing assignments 1 20 20
Preparing presentations 1 45 45
Final 1 3 3
Midterm 1 3 3
TOTAL WORKLOAD (hours) 218

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8
LO.11
LO.222
LO.33333
LO.4444
LO.55

CONTACT INFORMATION
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Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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