COURSE UNIT TITLE

: INTRODUCTION TO STRUCTURAL BIOLOGY

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
MBG 5037 INTRODUCTION TO STRUCTURAL BIOLOGY ELECTIVE 3 0 0 9

Offered By

Molecular Biology and Genetics

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

ASSISTANT PROFESSOR EZGI KARACA EREK

Offered to

Molecular Biology and Genetics
Molecular Biology and Genetics

Course Objective

To gain an understanding of biology through structural biology approaches.

Learning Outcomes of the Course Unit

1   1. Thorough knowledge on molecular complexes and their components
2   2. Familiarity with the three-dimensional structures of molecular complexes
3   3. Being able understand and discuss functioning of various molecular complexes
4   4. Being able understand and discuss the effect of oncogenic mutations on the functioning of molecular machines
5   5. Being able to discuss the capabilities and limitations of current design strategies
6   6. Presentation of research findings

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 The structural biology world
2 Protein structures
3 Nucleic Acid structures
4 Glycan and Lipid structures
5 The Process of Living: Energy and Entropy
6 Integral Molecular Complexes - I
7 Integral Molecular Complexes - II
8 Midterm
9 Signaling Complexes
10 Metabolic Complexes
11 The Effect of Oncogenic Mutations in structures
12 The Effect of Oncogenic Mutations in complexes
13 Predicting Biomolecular Complexes - I
14 Predicting Biomolecular Complexes - II
15 Assignment Presentations
16 Final Exam

Recomended or Required Reading

Machinery of Life, David Goodsell
Hardcover: 167 pages
Publisher: Copernicus; 2nd ed. 2009 edition (April 16, 2010)
Language: English
ISBN-10: 0387849246
ISBN-13: 978-0387849249

Introduction to Protein Structure, Carl Branden and John Tooze
Paperback: 424 pages
Publisher: Garland Science; 2 edition (January 3, 1999)
Language: English
ISBN-10: 9780815323051
ISBN-13: 978-0815323051

Lehninger Principles of Biochemistry
Hardcover: 1328 pages
Publisher: W.H. Freeman; Sixth edition (November 21, 2012)
Language: English
ISBN-10: 9781429234146
ISBN-13: 978-1429234146

Planned Learning Activities and Teaching Methods

Oral presentation, hands-on practicals, literature search and discussion

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 ASG ASSIGNMENT
2 MTE MIDTERM EXAM
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE ASG * 0.30 + MTE * 0.30 + FIN * 0.40
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) ASG * 0.30 + MTE * 0.30 + RST * 0.40


Further Notes About Assessment Methods

None

Assessment Criteria

Theoretical knowledge will be evaluated by exam

Language of Instruction

English

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

ezgi.karaca@deu.edu.tr

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 3 42
Preparations before/after weekly lectures 14 2 28
Preparation for final exam 1 30 30
Preparing assignments 2 20 40
Project Preparation 1 45 45
Preparing presentations 2 15 30
Final 1 5 5
TOTAL WORKLOAD (hours) 220

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8
LO.1554
LO.2444
LO.3444
LO.4444
LO.54444
LO.6444

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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