COURSE UNIT TITLE

: ADVANCED MOLECULAR AND CELL BIOLOGY

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
MBG 6101 ADVANCED MOLECULAR AND CELL BIOLOGY ELECTIVE 3 0 0 15

Offered By

Molecular Biology and Genetics

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

ASSOCIATE PROFESSOR MUHAMMED KASIM DIRIL

Offered to

Molecular Biology and Genetics
Molecular Biology and Genetics

Course Objective

To have a comprehensive understanding and advanced level knowledge about (i) proteins: structure and functions, (ii) fundemental molecular genetic mechanisms including DNA replication, transcription, translation, gene expression, genome organization, (iii) cell signaling, (iv) cell membrane: physicochemical characteristics, origins, composition, organization and functions, (v) cytoplasmic filamets: structure, organization, characteristics and functions, (vi) regulation of the ekaryotic cell cycle and apoptosis, (vii)) extracellular matrix: composition and functions, (viii) cancer.

Learning Outcomes of the Course Unit

1   To understand the structure and functions of proteins
2   To gain knowledge about basic molecular genetic mechanisms such as replication, transcription, translation, gene expression, genome organization
3   To learn how intracellular and intercellular signal transmission occurs
4   To have advanced knowledge about the physicochemical properties of the membrane that holds eukaryotic cells together, the origin, content, organization and functions of the organelles that make up the cell
5   To understand how cytoplasmic filaments organize cell organelles and their function in cell division
6   To understand how cell division and cell death are controlled, and the roles of these processes in cancer
7   To gain advanced knowledge about extracellular matrix and tissue organization
8   To describe cancer and genetic processes that lead to cancer

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Proteins (Structure and functions)
2 DNA, Chromosomes and Genomes
3 DNA Replication, Repair, and Recombination
4 How Cells Read the Genome: From DNA to Protein
5 Control of Gene Expression
6 Membrane Structure
7 Membrane Transport of Small Molecules and the Electrical Properties of Membranes
8 Intracellular Compartments and Protein Sorting
9 MIDTERM
10 Intracellular Membrane Traffic
11 Cell Signaling
12 The Cytoskeleton
13 The Cell Cycle and Cell Death
14 Cell Junctions and the Extracellular Matrix
15 Cancer
16 Final Exam

Recomended or Required Reading

Textbook(s): Molecular Biology of the Cell. by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter. Garland Science. 6th edition, 2014.
ISBN: 9780815344322
Supplementary Book(s): Molecular Cell Biology by Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Matthew P. Scott. W. H. Freeman & Co., 7th edition, 2012.
ISBN-13: 978-1429234139
References:
Materials:

Planned Learning Activities and Teaching Methods

Theoretical lectures with PowerPoint presentations and journal club presentations and discussion

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 ASG ASSIGNMENT
2 MTE MIDTERM EXAM
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE ASG * 0.30 + MTE * 0.30 + FIN * 0.40
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) ASG * 0.30 + MTE * 0.30 + RST * 0.40


Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

English

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

kasim.diril@deu.edu.tr
26559

Office Hours

Thursday 16.00-17.00

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 3 42
Preparations before/after weekly lectures 14 5 70
Preparation for midterm exam 1 30 30
Preparation for final exam 1 45 45
Preparing assignments 2 30 60
Preparing assignments 2 30 60
Preparing presentations 2 30 60
Final 1 4 4
Midterm 1 4 4
TOTAL WORKLOAD (hours) 375

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8
LO.12
LO.22
LO.32
LO.42
LO.52
LO.62
LO.72
LO.82

CONTACT INFORMATION
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Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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