COURSE UNIT TITLE

: FUNDAMENTALS OF BIOPHOTONICS

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
MBG 6128 FUNDAMENTALS OF BIOPHOTONICS ELECTIVE 3 0 0 12

Offered By

Molecular Biology and Genetics

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

ASSOCIATE PROFESSOR SERHAT TOZBURUN

Offered to

Molecular Biology and Genetics
Molecular Biology and Genetics

Course Objective

Two-fold; (1) to develop a fundamental understanding of modern and classical optics, light-tissue interaction, laser treatment and optical sensing for diagnostic and monitoring, and (2) to provide graduate students a broad overview on the cutting-edge researches in the area of biomedical optics.

Learning Outcomes of the Course Unit

1   The students will understand the basic optics.
2   The students will appreciate novel technologies and applications from cutting-edge research projects in biomedical optics.
3   The students will be able to describe the principles of light propagation in biological tissue.
4   The students will be able to discuss the basics of lasers in medicine.
5   The students will be able to list the major optical imaging methods in biomedical practice and research.
6   The students will be able to explain the principles of light-tissue interactions.
7   The students will understand the advantages and limitations of current optical methods for diagnostic and therapy in medical applications.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Nature of light
2 Basics of lasers and laser optics
3 Optical properties of tissue
4 Introduction to laser-tissue interactions
5 Laser ablation therapy
6 Low level laser therapy
7 Laser photocoagulation therapy
8 Theory of Rayleigh light scattering and Mie light scattering
9 MIDTERM
10 Introduction to optical imaging
11 Ballistic imaging, Diffuse optical tomography, and photoacoustic tomography
12 Optical coherence tomography
13 Optical spectroscopy: Fluorescence spectroscopy and Infrared spectroscopy
14 Optical microscopy: Confocal microscopy and multi-photon microscopy
15 Principles of optical biosensors and fiber-optic biosensors
16 Final exam

Recomended or Required Reading

Textbook(s): There is no single textbook available which specifically addressing the topics in the course. There are supplementary books, which include all material for this course comprehensively. Class notes will be available to students online by the links associated with each week.

Supplementary Book(s):
1) Biomedical Optics: Principles and Imaging by Lihong V. Wang and Hsin-i Wu; Wiley-Interscience, 1st edition, 2007. ISBN-13: 978-0471743040
2) Biomedical Photonics Handbook by Tuan Vo-Dinh (Editor-in-Chief); CRS Press, 1st edition, 2003. ISBN-13: 978-0849311161
3) Optics by Eugene Hecht; Addison-Wesley, 4th edition, 2001. ISBN-13: 978-0805385663
4) Introduction to Biophotonics by Paras N. Prasad; Wiley-Interscience, 1st edition, 2003. ISBN-13: 978-0471287704

Planned Learning Activities and Teaching Methods

Discussion, active participation by students, individualized, theoretical studies, and literature review.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 ASG ASSIGNMENT
2 MTE MIDTERM EXAM
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE ASG * 0.30 + MTE * 0.30 + FIN * 0.40
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) ASG * 0.30 + MTE * 0.30 + RST * 0.40


Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

English

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Email: serhat.tozburun@deu.edu.tr
Phone: 4126538

Office Hours

TBA

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 15 2 30
Tutorials 15 2 30
Preparations before/after weekly lectures 15 4 60
Preparation for midterm exam 1 15 15
Preparation for final exam 1 25 25
Preparing assignments 1 30 30
Preparing assignments 1 40 40
Preparing presentations 15 5 75
Final 1 2 2
Midterm 1 3 3
TOTAL WORKLOAD (hours) 310

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8
LO.12
LO.22
LO.32
LO.42
LO.52
LO.62
LO.72