COURSE UNIT TITLE

: THE BASIS OF MOLECULAR MEDICINE I

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
MOT 6053 THE BASIS OF MOLECULAR MEDICINE I COMPULSORY 2 0 0 6

Offered By

Molecular Medicine

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR DOCTOR GÜL HÜRAY IŞLEKEL

Offered to

Molecular Medicine
Molecular Medicine

Course Objective

Understanding of cell organization and function. Teaching the biomolecules playing roles in living organisms and their functions. The metabolic pathways and their regulations are also included by the course.

Learning Outcomes of the Course Unit

1   To get know about history of molecular medicine.
2   Describes the molecular structure and organization of cells
3   To get know about molecular components (carbohydrates, lipids, proteins, enzymes, nucleic acids) and chemistry of the cell.
4   Outlines basic metabolic processes.
5   Explains the processes of genetic information transfer (replication/transcription/translation/ the formation of functional protein)
6   To have general knowledge about basic molecular and cellular mechanisms related to diseases.
7   To be able to get and discuss the articles related subject areas.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 The history of molecular medicine
2 Organelles of the cell and their structures and functions
3 Cell Cycle, Growth and Differentiation
4 Structure and Functions of Biomolecules-I (Carbohydrates, Lipids)
5 Structure and Functions of Biomolecules-II (Proteins, Enzymes)
6 Structure and Functions of Biomolecules-III (Nucleic acids, Vitamins)
7 The integration of the metabolism
8 MID-TERM
9 Genes and DNA
10 Genomic DNA replication , protection, reorganization and its relationship with disease
11 RNA synthesis and processing , transcription, regulation of transcription
12 Protein synthesis , processing and regulation of gene expression and its role in diseases
13 Definition and types of mutations , single-gene mutations , polymorphisms , genetic and epigenetic control mechanisms
14 Genetic disorders
15 Identification of disease-related genes
16 FINAL

Recomended or Required Reading

Textbook(s):
Lodish, Berk, Matsudaira, Kaiser, Krieger, Scott, Zipursky, Darnell , Molecular Cell Biology
Alberts, et al. Molecular Biology of the Cell , Fifth ed., Garland Sciences.
Supplementary Book(s):
Marks Basic Medical Biochemistry, A Clinical Approach. Michael Lieberman, Allan D. Marks
Lehninger Principles of Biochemistry 5th Edition,David L. Nelson, Michael M. Cox.
Materials: Articles and reviews about course subjects.

Planned Learning Activities and Teaching Methods

Course will be performed by a series of presentations which include theriotecal knowledge. It is accepted that students should read about presentation subjects before coming to classroom.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 FIN FINAL EXAM
3 FCG FINAL COURSE GRADE MTE * 0.40 + FIN* 0.60
4 RST RESIT
5 FCGR FINAL COURSE GRADE MTE * 0.40 + RST* 0.60


Further Notes About Assessment Methods

None

Assessment Criteria

Understanding, learning, analyse, compare, actively contribution

Language of Instruction

Turkish

Course Policies and Rules

Actively contribution in class

Contact Details for the Lecturer(s)

e-mail: huray.islekel@deu.edu.tr
Phone: 412 44 08

Office Hours

Tuesday 12.30-13:30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 3 42
Preparations before/after weekly lectures 14 3 42
Preparation for midterm exam 1 33 33
Preparation for final exam 1 33 33
TOTAL WORKLOAD (hours) 150

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12PO.13PO.14
LO.145445545445
LO.245445545445
LO.345545545445
LO.445545544445
LO.545545554445
LO.645545554445
LO.745545554445

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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