COURSE UNIT TITLE

: THE BASIS OF MOLECULAR MEDICINE II

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
MOT 6055 THE BASIS OF MOLECULAR MEDICINE II COMPULSORY 2 0 0 6

Offered By

Molecular Medicine

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR DOCTOR GÜL HÜRAY IŞLEKEL

Offered to

Molecular Medicine
Molecular Medicine

Course Objective

To understand cell behaviour at molecular level, molecular basis of genetic disorders and cancer, stem cell, immunology, genomics, bioinformatics and proteomics.

Learning Outcomes of the Course Unit

1   To have general knowledge about biological communication, signal transduction and control, cell cycle and cell death.
2   Describes the molecular basis of endocrine diseases.
3   Describes the molecular basis of cancer.
4   Describes the molecular basis of immunology and pathology.
5   To get know about human stem cells, human genome projects and contributions to medicine.
6   To have general knowledge about bioinformatic databases and their usage.
7   To have general knowledge about genomics,pharmacogenomics, proteomics and their applications.
8   To be able to get and discuss the articles related subject areas.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Biological communication ( Neurotransmitters, hormones, signal transduction)e
2 Molecular diagnosis of endocrine diseases
3 Molecular oncology-1
4 Molecular oncology-2
5 Stem cells
6 Medical Applications of Stem Cells
7 Overview of Immune System for Molecular Medicine-1
8 Overview of Immune System for Molecular Medicine-2
9 MID-TERM
10 Current Approaches in Molecular Pathology-1
11 Current Approaches in Molecular Pathology-2
12 Genomics and bioinformatics tools (Entrez, Ensemble, OMIM, GSEA, PDB, Blast, KEGG)
13 Human genome projects and contributions to medicine
14 Pharmacoogenetic/ Pharmacoogenomics
15 Proteomics and Applications
16 FINAL

Recomended or Required Reading

Textbook(s):
Lodish, Berk, Matsudaira, Kaiser, Krieger, Scott, Zipursky, Darnell , Molecular Cell Biology
Alberts, et al. Molecular Biology of the Cell , Fifth ed., Garland Sciences.
Supplementary Book(s):
Marks Basic Medical Biochemistry, A Clinical Approach. Michael Lieberman, Allan D. Marks
Lehninger Principles of Biochemistry 5th Edition,David L. Nelson, Michael M. Cox.

Materials: Articles and reviews about course subjects.

Planned Learning Activities and Teaching Methods

Course will be performed by a series of presentations which include theriotecal knowledge. It is accepted that students should read about presentation subjects before coming to classroom.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 PRF PERFORMANCE
2 FIN FINAL EXAM
3 FCG FINAL COURSE GRADE PRF * 0.40 + FIN*0.60
4 RST RESIT
5 FCGR FINAL COURSE GRADE (RESIT) PRF * 0.40 + FCGR*0.60


Further Notes About Assessment Methods

None

Assessment Criteria

Understanding, learning, analyse, compare, actively contribution

Language of Instruction

Turkish

Course Policies and Rules

Actively contribution in class

Contact Details for the Lecturer(s)

e-mail: huray.islekel@deu.edu.tr
Phone: 412 44 08

Office Hours

Tuesday 12.30-13:30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 3 42
Preparations before/after weekly lectures 14 3 42
Preparation for midterm exam 1 33 33
Preparation for final exam 1 33 33
TOTAL WORKLOAD (hours) 150

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12PO.13PO.14
LO.15555545455
LO.25555545455
LO.35555545455
LO.45555545455
LO.55555545455
LO.65555545455
LO.7555555545455
LO.85555555555