COURSE UNIT TITLE

: BIOBANK

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
MOT 6043 BIOBANK ELECTIVE 2 0 0 6

Offered By

Molecular Medicine

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR DOCTOR HILAL KOÇDOR

Offered to

Molecular Medicine
Molecular Medicine

Course Objective

Biobanks are current and important infrastructure blocks in terms of health sciences today.
This course aims to introduce the importance of biobanking and the components of biobanking.
Biobanks have transformed from simple biological sample repositories to complex and dynamic units.
In biobanks, many researchers and health professionals working in different fields collaborate to obtain biological samples and collect relevant data.
Biobanks are professional structures. Workflows are organized with strict rules.
This course will include creating high-quality medical record systems, connecting large databases to each other, and increasing students' awareness of the necessary regulations regarding ethical issues that may be encountered in the biobanking process.
Biobanks are governed by legal regulations.
This course aims to discuss the legal and ethical regulations mentioned in biobanking as well as the difficulties encountered.

Learning Outcomes of the Course Unit

1   To have basic theoretical knowledge about the storage of biological samples and critically discuss with others
2   To have information about the techniques to be used in studies on biobanks.
3   Ability to critically analyze information
4   Ability to evaluate and comment on research in the field of biobanks
5   Ability to access databases related to biobanking and use the information obtained
6   Ability to apply basic laboratory techniques
7   To gain the ability to follow current developments regarding international legal regulations applied on biobanks
8   Understanding the systematics of ethical regulations on biobanking and being able to follow the process

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 * Introducing the concept of biobanking,
2 * Current discussion of international legal and ethical regulations on biobanking,
3 * Operation and management structures of biobanks, equipment, * Obtaining, processing and storing biological samples in biobanking, banking principles, database management systems,
4 * Access to samples in biobanking, workflow rules,
5 * Tissue, organ banks, cell banks, DNA banks, * Disease-specific biobanks, commercial biobanks, biobanks providing community genetic data, forensic biobanks,
6 * Storage and banking of pathological samples, on-site observation of similar practical applications,
7 * On-site monitoring of blood banking and its practices,
8 * Bone marrow biobanking * Cord blood banking
9 * Stem Cell Biology Banking, * Preparation of a biobank installation and operation simulation,
10 * Project presentation

Recomended or Required Reading

* Hewitt R, Watson P (October 2013). "Defining biobank". Biopreservation and Biobanking. 11 (5): 309 15. doi:10.1089/bio.2013.0042. PMID 24835262.
*Cambon-Thomsen A, Rial-Sebbag E, Knoppers BM (August 2007). "Trends in ethical and legal frameworks for the use of human biobanks". The European Respiratory Journal. 30 (2): 373 82. doi:10.1183/09031936.00165006. PMID 17666560. S2CID 15217640.
*Hewitt RE (January 2011). "Biobanking: the foundation of personalized medicine". Current Opinion in Oncology. 23 (1): 112 9. doi:10.1097/CCO.0b013e32834161b8. PMID 21076300. S2CID 205547716.
*Paskal W, Paskal AM, D bski T, Gryziak M, Jaworowski J (October 2018). "Aspects of Modern Biobank Activity - Comprehensive Review". Pathology & Oncology Research. 24 (4): 771 785. doi:10.1007/s12253-018-0418-4. PMC 6132819. PMID 29728978.
*Riegman PH, Morente MM, Betsou F, de Blasio P, Geary P, et al. (Marble Arch International Working Group on Biobanking for Biomedical Research) (October 2008). "Biobanking for better healthcare". Molecular Oncology. 2 (3): 213 22. doi:10.1016/j.molonc.2008.07.004. PMC 5527804. PMID 19383342
* Gottweis H, Petersen AR (20 June 2008). Biobanks: governance in comparative perspective. Taylor & Francis. p. 92. ISBN 978-0-415-42737-1. Retrieved 1 February 2012
* Jan-Eric Litton, Biobank Informatics: Connecting Genotypes and Phenotypes Methods in Biobanking p.343-361
*http://www.cryolab.com/reasons.shtml
* Labant MA (Jan 15, 2012). "Biobank Diversity Facilitates Drug & Diagnostic Development". Genetic Engineering & Biotechnology News. 32 (2): 42,44. doi:10.1089/gen.32.2.21. ISSN 1935-472X. Retrieved 1 February 2012
*TCK Madde 90: Insan üzerinde deney (Article 90: Human trials on the Turkish Penal Code)
*Organ ve doku nakli hizmetleri yönetmeliği (Organ and tissue transplantation sevices regulation)
*TC. Sağlık Bakanlığı AÇS ve Aile Planlaması Genel Müdürlüğü, Üremeye yardımcı Tedavi Merkezleri Yönetmeliği. (Turkish Ministry of Health, assited reproductive medicine regulation)
*TC. Sağlık Bakanlığı, Kordon kanı bankacılığı yönetmeliği (Turkish Ministry of Health, cord blood banking regulation)

Planned Learning Activities and Teaching Methods



Although the course is theoretical, it will be prepared and presented in the form of case discussions and these activities will be handled together with both students and instructors.
The course will be taught with interactive methods.
Students are expected to come to the course prepared in advance by using the resources and guidance provided.
Methods: interactive presentations, group work, group discussions, student presentations, live visits of sample applications on site.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 PRF PERFORMANCE
2 FCG FINAL COURSE GRADE PRF


Further Notes About Assessment Methods

As interactive manner, lectures will be handled with their theoric bases and structured-case-studies. Students are expected to be read lecture notes given by course coordinators before the lecture
Methods: Interactive presentations, group discussions, student presentations and prepared project presentations.

Assessment Criteria




The courses will be handled interactively with theoretical foundations and structured studies.

The efficiency of the course based on interactive study: Since there is a structuring in the course on existing knowledge, students are expected to come to the course energetic, motivated and prepared with theoretical knowledge.

Students are expected to come to the course by preparing the topics and details suggested by the course coordinators before the course.

Methods: Interactive presentations, group discussions, student presentations and prepared project presentations.

Language of Instruction

Turkish

Course Policies and Rules


Before the classes, students should prepare to gain knowledge about the substructure of the subject.

Doctoral courses are areas where discussion of the higher level of knowledge on the subject is necessary.

Contact Details for the Lecturer(s)



Course Coordinator:
Prof. Dr. Hilal KOÇDOR

DEU.Oncology Institute
Basic Oncology Department
hilal.kocdor@deu.edu.tr
h.kocdor@gmail.com

0 232 4125803

Office Hours




Every weekday;
13.00

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 30 1 30
Preparations before/after weekly lectures 15 2 30
Field study 5 5 25
Preparing presentations 5 4 20
Preparing report 1 45 45
TOTAL WORKLOAD (hours) 150

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12PO.13PO.14
LO.15
LO.25
LO.3555
LO.45555
LO.55555
LO.65555
LO.75
LO.8