COURSE UNIT TITLE

: INTRODUCTION TO MOLECULAR MEDICINE II

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
MOT 5026 INTRODUCTION TO MOLECULAR MEDICINE II COMPULSORY 3 0 0 6

Offered By

Molecular Medicine

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

ASSOCIATE PROFESSOR YASEMIN SOYSAL

Offered to

Molecular Medicine
Molecular Medicine

Course Objective

To understand the molecular basis of cell behavior, genetic diseases and cancer at the molecular level, and their use in stem cells, immunology, genomics, bioinformatics, proteomics and medicine.

Learning Outcomes of the Course Unit

1   Explains cytoskeleton, cell-cell, cell-environment interactions and their relationship with diseases.
2   Knows the basic concepts of signal transduction-control and cell life cycle and death.
3   Describes the molecular basis of cancer and immunology.
4   Gains knowledge of molecular genetic concepts and gene discovery in diseases.
5   Learn about stem cells, human genome projects and their contributions to medicine.
6   Have general knowledge about bioinformatics databases and their usage.
7   To have general knowledge about genomics, proteomics and their applications.
8   Gains knowledge of accessing and discussing articles related to course topics.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Heredity, Genes and DNA
2 Replication, Conservation, Rearrangement of Genomic DNA
3 RNA Synthesis and Processing, Transcription, Regulation of Transcription
4 Protein Synthesis, Processing and Regulation-Gene Expression
5 Definition of mutation and Types, Single Gene Mutations, Polymorphism
6 Epigenetic Control Mechanisms
7 Inheritance patterns in genetics
8 MID-TERM
9 Hormones; General Properties and Mechanisms of Effect
10 Molecular Basis of Genetic Diseases
11 Molecular Basis of Endocrine Diseases
12 Immunology for Molecular Medicine
13 Molecular Organization in Tissue Level
14 Molecular Basis of Cancer
15 Fundamentals of Molecular Pharmacology
16 FINAL

Recomended or Required Reading

Textbook(s):
Lodish, Berk, Matsudaira, Kaiser, Krieger, Scott, Zipursky, Darnell , Molecular Cell Biology
Alberts, et al. Molecular Biology of the Cell , Fifth ed., Garland Sciences.
Supplementary Book(s):
Marks Basic Medical Biochemistry, A Clinical Approach. Michael Lieberman, Allan D. Marks
Lehninger Principles of Biochemistry 5th Edition,David L. Nelson, Michael M. Cox.
References:
Materials: Articles and reviews about course subjects.

Planned Learning Activities and Teaching Methods

The course is theoretical. It takes place in the form of presentations. The student is expected to come to the lesson having read the given resources.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 ASG ASSIGNMENT
3 FIN FINAL EXAM
4 FCGR FINAL COURSE GRADE MTE * 0.30 + ASG * 0.20 + FIN* 0.50
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.30 + ASG * 0.20 + RST* 0.50


Further Notes About Assessment Methods

None

Assessment Criteria

Comprehension, learning, analysis, comparison, interactive participation

Language of Instruction

Turkish

Course Policies and Rules

Actively contribution in class

Contact Details for the Lecturer(s)

e-mail: yasemin.soysal@deu.edu.tr
Phone: 412 6905

Office Hours

Tuesday, 12:30-13:30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 3 42
Preparation for midterm exam 1 33 33
Preparation for final exam 1 33 33
Preparation before/after weekly lectures 14 3 42
TOTAL WORKLOAD (hours) 150

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12PO.13PO.14
LO.15555545455
LO.25555545455
LO.35555545455
LO.45555545455
LO.55555545455
LO.65555545455
LO.7555555545455
LO.85555555455